The database distinguishes itself from other protein sequence databases by three criteria: (i) annotations, which cover a broad range of information, (ii) minimal redundancy, which ensures that each sequence is represented only once, and (iii) integration with other databases, which enables cross-...
Example. A few popular databases are GenBank from NCBI (National Center for Biotechnology Information), SwissProt from the Swiss Institute of Bioinformatics and PIR from the Protein Information Resource. Table of Contents Types of Biological Databases 1. Primary databases 2. Secondary databases Importanc...
A comprehensive analysis of different types of databases reveals thatCDH1mRNA and E-cadherin protein are not downregulated in most carcinoma tissues and carcinoma cell linesCELL linesCADHERINSMESSENGER RNAGENE expressionADHERENS junctionsBackground: The CDH1 gene codes for the epithelial-cadherin (E-cad)...
W. et al. Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging. Preprint at https://arxiv.org/abs/2107.07953 (2021). Manz, T. et al. Viv: multiscale visualization of high-resolution multiplexed bioimaging data on the web. Preprint at...
To aid the assessment and understanding of these variations, population databases such as gnomAD [1], ExAC [2], and ChinaMap [3] have been established. Additionally, genetic disease databases, e.g., ClinVar [4], OMIM [5], and HGMD [6], have also amassed a large amount of information...
W. et al. Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging. Preprint at https://arxiv.org/abs/2107.07953 (2021). Manz, T. et al. Viv: multiscale visualization of high-resolution multiplexed bioimaging data on the web. Preprint at...
Benchmarking Universal Single-Copy Orthologs (BUSCO) evaluation showed that the gene set completeness of the R108 genome was comparable to that of the A17 genome (Mt5.0), in that more than 98% of all BUSCOs were successfully annotated (Table S4). Five protein databases–InterPro, KEGG, ...
Due to insufficiency of the fish protein databases, we still have a lot of peptides, which can not match any known proteins. Fish species have their special gene pools including swamp eel. 2D resolution is not precise enough, for example, Rab37 identified from ovary-only spots is expressed ...
(adenocarcinoma vs. squamous cell carcinoma) and mutational state of the protein, C-K-RAS (KRAS) and the epidermal growth factor receptor (EGFR) gene. When considering the whole cancer genome, taking into consideration the preponderance of DNA alteration or specific mutations is the key to ...
Primary databases are a type of biological database that contain original and unprocessed biological data.These databases typically consist of raw sequences, such as nucleotide or protein sequences, or structural information, such as molecular structures. ...