答案是:阶梯设计(the stepped-wedge design) 阶梯设计多用于整群随机试验,评价“利大于弊”的干预措施,尤其在健康教育、免疫接种、筛检、医护人员培训等领域使用较多。这种设计通常不设置专门的对照组,随着试验的进行,各个组都会按照随机结果先后接受这种干预措施。这样就...
We used a stepped-wedge design, evaluating the proportion of potentially undertreated patients with AF started on anticoagulant therapy within 28 days for clinics randomised to intervention versus usual care. Results Of 1727 algorithm-identified high-risk patients with AF in clinics at the time of ...
In contrast, there is little research available pertaining to the design and analysis of multi-arm stepped-wedge cluster randomized trials, utilized to evaluate the effectiveness of multiple experimental interventions. In this paper, we address this by explaining how the required sample size in these...
Using a cluster-randomized stepped-wedge type-2 hybrid effectiveness-implementation design, we will test: (a) the implementation impact of Opioid Court REACH in improving implementation outcomes along the opioid cascade of care (screening, referral, treatment enrollment, MOUD initiation), and (b) ...
The study employs a stepped-wedge cluster-randomised controlled community trial design in 16 communities over fivemonthly visits. During each visit, we will collect data on participants' source of drinking and cooking water and measure the salinity level and electrical conductivity of household stored ...
This study will also include up to 3 control sites (Fig.1a), a feature not typically included with historic stepped-wedge trial designs, which will strengthen our ability to understand external influences on the study findings. These control sites, which do not receive the CDS intervention and ...
The analysis of data from such a design involves the comparison of the intervention “wedge” (i.e., data from the clusters that have received the intervention during a step) with the control wedge... ... Access to the complete content on Oxford Reference requires a subscription or purchas...
Stepped wedge trials are randomized trials in which each randomization unit first receives the control condition and then crosses over to receive the intervention. However, the time at which the intervention is provided to each unit is randomized. Stepped wedge trials may be either individually or ...
In a stepped wedge, cluster randomised trial, clusters receive the intervention at different time points, and the order in which they received it is randomised. Previous systematic reviews of stepped wedge trials have documented a steady rise in their use between 1987 and 2010, which was attribute...
The analysis of data from such a design involves the comparison of the intervention “wedge” (i.e., data from the clusters that have received the intervention during a step) with the control wedge... ... Access to the complete content on Oxford Reference requires a subscription or purchas...