Stepped wedge cluster randomised trials (SW-CRTs) are being used with increasing frequency in health service evaluation. Conventionally, these studies are designed with equally spaced steps, with an equal number of clusters randomised at each step, and data collected at each and every step. Here ...
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In contrast, there is little research available pertaining to the design and analysis of multi-arm stepped-wedge cluster randomized trials, utilized to evaluate the effectiveness of multiple experimental interventions. In this paper, we address this by explaining how the required sample size in these...
The use of Stepped Wedge cluster randomized trials: Systematic Review Dr Celia Taylor The University of Birmingham On behalf of my co-authors: Noreen Mdege, Mei-See Man and David Torgerson (University of York) Today’s presentation What is a stepped wedge design? What are the advantages and...
The study employs a stepped-wedge cluster-randomised controlled community trial design in 16 communities over fivemonthly visits. During each visit, we will collect data on participants' source of drinking and cooking water and measure the salinity level and electrical conductivity of household stored ...
Stepped wedge cluster randomized controlled trials (RCTs) are increasingly used in evaluating a causal-effect relationship between an intervention and an outcome. Sample size and power calculations are critical in designing a statistical study. Thus, the purpose of our study is to evaluate the power...
cluster size variationcross‐sectionalpowersample sizestepped wedgeStandard sample size calculation formulas for stepped wedge cluster randomized trials (SW〤RTs) assume that cluster sizes are equal. When cluster sizes vary substantially, ignoring this variation may lead to an under﹑owered study. We ...
If the cluster sizes are all equal, a two-sample t-test may be used to compare cluster-level mean responses between the intervention groups. If there are more than 2 treatment arms, a one-way analysis of variance may be used. Sometimes the communities are matched and randomization is done...
The stepped-wedge cluster randomized design has been increasingly employed by pragmatic trials in health services research. In this study, based on the GEE approach, we present closed-form sample size calculation that is applicable to both closed-cohort and cross-sectional stepped wedge trials. Impor...
To describe the application of the stepped wedge cluster randomized controlled trial (CRCT) design. Systematic review. We searched Medline, Embase, PsycINFO, HMIC, CINAHL, Cochrane Library, Web of Knowledge, and Current Controlled Trials Register for articles published up to January 2010. Stepped we...