Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation. J. Biol. Chem. 282, 20728-20738, doi: 10.1074/jbc.M703292200 (2007).Splicing factor3b subunit4binds BMPR-IA andinhibits osteochondral cell differentiation. Watanabe H,Shionyu M,Kimura T, et al. Journal...
Bone morphogenetic protein (BMP)-2/4 play critical roles in early embryogenesis and skeletal development. BMP-2/4 signals conduct into cells via two types of serine/threonine kinase receptors, known as BMPR-I (IA and IB) and BMPR-II. Here we identified splicing factor 3b subunit 4 (SF3b4...
et al. Mutant splicing factor 3b subunit 1 (SF3B1) causes dysregulated erythropoiesis and a stem cell disadvantage. Blood Abstr. 124, 828 (2014). Article Google Scholar Mupo, A. et al. Sf3b1 K700E mutation impairs pre-mRNA splicing and definitive hematopoiesis in a conditional knock-in ...
pyrimidine-rich RNA may contribute to the selection of specific splice sites97. U2AF65 and its related protein CAPERα (also known as RBM39) show cooperative binding to splicing factor 3b subunit 1 (SF3B1). U2AF65 forms liquid-like condensates through its SR-rich domain, and condensation is...
The transcription factor forkhead box P2 (FOXP2) is of particular interest as a potential driver of human language function, as it harbors two amino acid substitutions present in humans but not in chimpanzees and many other mammalian genomes. Families with FOXP2 mutations exhibit severe speech defe...
a crucial subunit of SF3B [32], participates in pre-mRNA splicing while concurrently regulating cellular signal transduction, transcription, and translation [33]. Notably, SF3B4 is abnormally overexpressed in ovarian cancer, promoting ovarian cancer cell proliferation, migration, and invasive ability and...
Hou et al., reported that the mutations in the splicing factor 3B subunit 1 (SF3B1), U2 small nuclear RNA auxiliary factor 2 (U2AF1), and serine and arginine rich splicing factor 2 (SRSF2), had an independent role in disease progression (Hou et al., 2016). Abnormal expression or ...
Splicing factor 3b, subunit 1 SRSF2: Serine/arginine-rich splicing factor 2 U2AF1: U2 small nuclear RNA auxiliary factor 1 BCL-2: B cell lymphoma 2 IAP: Inhibitor of apoptosis BIM: Bcl-2-like protein 11 SRSF1: Serine/arginine-rich splicing factor 1 mTORC1: Mammalian target of...
英文名称: SF3B2 (Splicing Factor 3B Subunit 2, Cus1, SF3b1, SAP145, SF3B145, SF3b150) (HRP) 英文同义词: SF3B2 (Splicing Factor 3B Subunit 2, Cus1, SF3b1, SAP145, SF3B145, SF3b150) (HRP) CAS号: 分子式: 分子量: 0 EINECS号: 信息错误报告 您的Email: 按...
UTR region J Kim1, RY Park2, J-K Chen3, J Kim3, S Jeong*,1 and T Ohn*,2 Serine/arginine-rich splicing factor 3 (SRSF3), a member of the serine/arginine (SR)-rich family of proteins, regulates both alternative splicing of pre-mRNA and export of mature mRNA from the nucleus. ...