Using this approach, we found that an inhibitor of splicing factor 3B subunit 1 (SF3B1), called sudemycin D6, is a potent inhibitor of HIV transcription and reactivation. SF3B1 is part of the U2 snRNP complex required for mRNA splicing (8–10). Although SF3B1 is traditionally recognized ...
Amplification and detection of the candidate genes and of three reference genes (Splicing factor 3a, subunit 1 (SF3A1), Proteasome 26S subunit ATPase 4 (PSMC4), Pumilio homolog 1 (PUM1)) were conducted with a Realplex 2 Master Cycler (Eppendorf, Mississauga, Canada). We investigated the ...
Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1) Felicia Fei-Lei Chung, Perry Faith Tze Ming Tan, Vijay Joseph Raja, Boon-Shing Tan, Kuan-Hon Lim, Toh-Seok Kam, Ling-Wei Hii, Si Hoey Tan, Sze-Jia See, Yuen-Fen...
Splicing factor 3b, subunit 1 SRSF2: Serine/arginine-rich splicing factor 2 U2AF1: U2 small nuclear RNA auxiliary factor 1 BCL-2: B cell lymphoma 2 IAP: Inhibitor of apoptosis BIM: Bcl-2-like protein 11 SRSF1: Serine/arginine-rich splicing factor 1 mTORC1: Mammalian target of...
Hou et al., reported that the mutations in the splicing factor 3B subunit 1 (SF3B1), U2 small nuclear RNA auxiliary factor 2 (U2AF1), and serine and arginine rich splicing factor 2 (SRSF2), had an independent role in disease progression (Hou et al., 2016). Abnormal expression or ...
RNA binding motif protein 4 (RBM4), an RNA-binding protein that shuttles between the nucleus and cytoplasm, serves as a splicing factor that modulates alternative splicing by binding to the RNA recognition motifs (RRMs) GTAACG or CGGCGG, functioning as a general splicing inhibitor (Fig.3A) [...
英文名称:Rabbit anti-human splicing factor 3a, subunit 3, 60kDa polyclonal Antibody,中文名称:兔抗人剪接因子3a,亚单位3,60kDa多克隆抗体,产品货号:MBS712571,[[其他大小:请联系我们订购其他不同大小的。[说明:此抗体需要在+4°C的冰箱中短期浓缩保存。
英文别名: SF3A3 (Splicing Factor 3A Subunit 3, PRP9, PRPF9, SF3a60, Spliceosome-associated Protein 61, SAP 61, SAP61) 中文名: 中文别名: CBNumber: CB35222781 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 SF3A3 (Splicing Factor 3A Subunit 3, PRP9, ...
The reduction in global protein synthesis could be attributed to a generalized stress response, which is facilitated by phosphorylation of the α subunit of the eukaryotic translation initiation factor 2 (eIF2α) at serine S5153. However, acSRSF1 HKO mice did not exhibit an increase in eIF2α...
Pre-mRNA processing factor AS : Alternative splicing RP : Retinitis Pigmentosa AID : Auxin-induced degradation RNAi : RNA interference SCF : Skp1-Cullin-F-box m.s. : Middle segment d.s. : Distal segment References Anvarian Z, Mykytyn K, Mukhopadhyay S, Pedersen LB, Christensen...