Known hypersensitivity to sotalol WARNINGS AND PRECAUTIONS Risk of life-threatening ventricular arrhythmias, particularly torsade de pointes (TdP). The risk of TdP can be reduced by adjustment of the sotalol dose according to creatinine clearance and by monitoring the ECG for excessive increases in QTc...
IV sotalol decreases the energy requirement in transthoracic atrial defibrillation,doi:10.2165/00128413-200012410-00052None
IV sotalol treatment should not be initiated if the baseline QTc is longer than 450ms. Reduce the dosage or discontinue if the interval extends to 500 ms or greater. Do not substitute one brand of sotalol for another without your doctor’s advice because of potentially significant differences in...
NYHA Classification was also closely associated to the incidence of new or worsened heart failure while receiving Sotalol (1.8% in 1395 Class I patients, 4.9% in 1254 Class II patients and 6.1% in 278 Class III or IV patients).Electrolyte Disturbances...
Introduction:Recently, an intravenous (IV) formulation of sotalol was approved to provide a loading dose before initiating oral sotalol therapy to reduce h... VK Yellepeddi,K Watt,K Ghaffari,... - 《Circulation》 被引量: 0发表: 2023年 Population pharmacokinetics and pharmacodynamics of sotalol ...
从1998年4月至2002年10月,该研究纳入的患者(n = 665)持续房颤持续至少72小时,并接受抗包衣疗法治疗,而国际标准化比率(INR)在2.0-3的范围内,使用dil-shazem,维拉帕米和地高辛将0的心室率保持在每分钟60-90内,患有房扑,阵发性房颤,NYHA III-IV级循环衰竭,肌酐清除率低于60 ml / min的患者被排除在研究之外...
Renal clearance (Clr) and intestinal clearance (Cli) of STL enantiomers were assessed in conscious Sprague–Dawley rats (325g, n =4) following administration of a 10mgkg1 IV dose of the racemate. STL enantiomers were predominantly eliminated intact in the urine: Clr for S- and R-STL (26...
Ibutilide fumarate is an intravenous (IV) class III antiarrhy... Annabelle,S,Volgman,... - 《Journal of the American College of Cardiology》 被引量: 612发表: 1998年 Ibutilide. A review of its pharmacological properties and clinical potential in the acute management of atrial flutter and ...
Methods:The using vitamin C inject 5 mg qd iv,bemegride inject 100 mg qd iv compared with Naloxone hydrochloride injection 0. 目的:观察比较贝美格(美解眠)注射液与盐酸纳洛酮注射液在治疗苯二氮卓类药物中毒的疗效。6) palonosetron hydrochloride injection 盐酸帕洛诺司琼注射液 1. RP-ion pair HPLC ...
IV sotalol is a new option but pediatric experience is limited. There is no standardized protocol for rapid infusion during acute arrhythmias. This study assessed a single center's initial experience with IV sotalol in young patients, describing a protocol for rapid infusion for acute treatment, ...