IV sotalol treatment should not be initiated if the baseline QTc is longer than 450ms. Reduce the dosage or discontinue if the interval extends to 500 ms or greater. Do not substitute one brand of sotalol for another without your doctor’s advice because of potentially significant differences in...
Known hypersensitivity to sotalol WARNINGS AND PRECAUTIONS Risk of life-threatening ventricular arrhythmias, particularly torsade de pointes (TdP). The risk of TdP can be reduced by adjustment of the sotalol dose according to creatinine clearance and by monitoring the ECG for excessive increases in QTc...
NYHA Classification was also closely associated to the incidence of new or worsened heart failure while receiving Sotalol (1.8% in 1395 Class I patients, 4.9% in 1254 Class II patients and 6.1% in 278 Class III or IV patients).Electrolyte Disturbances...