Do not substitute one brand of sotalol for another without your doctor’s advice because of potentially significant differences in labeling, dosing and administration, and safety information. Before taking sotalol You should not use sotalol if you are allergic to it, or any of the inactive ingredie...
2way to initiate sotalol for Atrial Fibrillation, Atrial Flutter, & Ventricular Tachycardia. Potentially shorten hospital stays and individualize treatment Resource Management Potentially increase bed availability, simplify patient management, and shorten loading regimen Consider a fast, efficient way to initiat...
Development of a Safe and Effective Pediatric Dosing Regimen for Sotalol Based on Population Pharmacokinetics and Pharmacodynamics in Children With Suprave... Objectives The objective of this study was to develop age-specific dosage guidelines for sotalol in children with supraventricular tachycardia (SVT...
This study assessed a single center's initial experience with IV sotalol in young patients, describing a protocol for rapid infusion for acute treatment, and reviewed the safety and efficacy of maintenance dosing. Methods This is a retrospective study of all patients who received IV sotalol at ...
Guidance for dosing in conditions of renal impairment can be found under DOSAGE AND ADMINISTRATION .Drug InteractionsDrugs undergoing CYP450 metabolism Sotalol is primarily eliminated by renal excretion; therefore, drugs that are metabolized by CYP450 are not expected to alter the pharmacokinetics of ...
Methods This is a single center retrospective study evaluating effective sotalol dosing from January 2011 and June 2021 (inclusive). Neonates who received intravenous (IV) or oral (PO) sotalol for SVT were eligible for inclusion. The primary outcome was to describe sotalol doses based on body ...
This population PK model could be used to correlate the PK with safety (QTc interval prolongation) further to optimize the sotalol IV and oral dosing regimen.Venkata K YellepeddiUniv of Utah, Salt Lake City, UTKevin WattPediatrics, Univ of Utah, UTKimia Ghaffari...
dysrhythmic effect (along with rapid activation of the collateral pathway, i.e., azygos vein direct blood delivery) might resolve the otherwise deadly course of the occlusion/occlusion-like syndrome as a whole in the rats with the maintained intra-abdominal hypertension, grade III and grade IV ...