Comparison of propranolol and sotalol pharmacokinetics in obese subjects. — Six obese subjects (mean ± s.d.: 145.1 ± 16.7% of ideal body weight) were randomly assigned to a single i.v. dose either of (±)-propranolol base (0.1... JM Poirier,CL Jeunne,G Cheymol,... - 《Journal ...
Introduction:Recently, an intravenous (IV) formulation of sotalol was approved to provide a loading dose before initiating oral sotalol therapy to reduce h... Venkata K Yellepeddi,Kevin Watt,Kimia Ghaffari,... - Circulation 被引量: 0发表: 2023年 Acute effects of d-amphetamine on progressive-ra...
The present invention provides a novel method of converting AF and monitoring normal sinus rhythm using an initial IV dose of sotalol followed by oral sotalol maintenance therapy. This method provides a method of acute assessment of QTc prolongation to determine the safety of chronic oral sotalol ...
The present invention provides a novel method of converting AF and monitoring normal sinus rhythm using an initial IV dose of sotalol followed by oral sotalol maintenance therapy. This method provides a method of acute assessment of QTc prolongation to determine the safety of chronic oral sotalol ...
The present invention provides a novel method of converting AF and monitoring normal sinus rhythm using an initial IV dose of sotalol followed by oral sotalol maintenance therapy. This method provides a method of acute assessment of QTc prolongation to determine the safety of chronic oral sotalol ...
In a placebo controlled open study in six healthy male volunteers (+)- sotalol in the dose range 0.125 mg kg-1-2.0 mg kg-1 intravenously, was found to have little or no beta-adrenoceptor blocking activity in comparison to the racemic mixture (+/-)-sotalol. The repolarization effects of ...