B. M. Venkatesan and R. Bashir, "Solid-State Nanopore Sensors for Nucleic Acid Analysis," Nanopores Sens. Fundam. Biol. Interact., 1 (2011).Venkatesan, B.M.; Rashid, B. Solid-state nanopore sensors for nucleic acid analysis. In Nanopores: Sensing and Fundamental Biological Applications;...
Nanopore-based sensors have established themselves as a prominent tool for solution-based, single-molecule analysis of the key building blocks of life, including nucleic acids, proteins, glycans and a large pool of biomolecules that have an essential role in life and healthcare. The predominant mol...
Imec provides a manufacturable nanopore platform on which single-molecule sensors can be built. Imec is actively looking for assay partners that can bring in the necessary chemistry know-how. These partners can test their applications on the minimal viable demonstrator (MVD) that imec is current...
Xue, L., Yamazaki, H., Ren, R.et al.Author Correction: Solid-state nanopore sensors.Nat Rev Mater5, 952 (2020). https://doi.org/10.1038/s41578-020-00256-x Download citation Published01 October 2020 Issue DateDecember 2020 DOIhttps://doi.org/10.1038/s41578-020-00256-x ...
来源学校 University of Illinois at Urbana-Champaign. 研究点推荐 Solid-state nanopore sensors Nanopore DNA analysis nucleic acid analysis 0关于我们 百度学术集成海量学术资源,融合人工智能、深度学习、大数据分析等技术,为科研工作者提供全面快捷的学术服务。在这里我们保持学习的态度,不忘初心,砥砺前行。了解更多>...
Conventional solid﹕tate nanopore sensors monitor the electrical pulses caused by molecules translocating through the nanopore. However, the electrical signal is limited by insufficient resolutions, low throughput, lack of specificity and molecule manipulation. Optical detection of single molecules has been ...
Dr. Ulrich Rant's research group has been doing the same for solid-statenanoporesensors, where the basic working principle is to urge biomolecules of interest, one at a time, through a nanometer-scale hole in a thin slab of semiconductor material. When biomolecules pass through or linger in ...
This enables nanopore-based detection of ssDNA fragments as short as 37 nt, which is normally very difficult with solid-state nanopore sensors, due to constraints in noise and bandwidth. Notably, this fragment is considerably shorter than the 65 nt binding motif, typically required for SSB ...
Potential applications: nanopore sensors and reactors The original idea of nanopore sensing was to use solid-state or biological pores as nanoscale analogs of Coulter counters to detect and analyze single molecules in liquids. Here, we review the developments of practical nanopore sensors and devices ...
Nanopore-based sensors are advancing the sensitivity and selectivity of single-molecule detection in molecular medicine and biotechnology. Current electrical sensing devices are based on either membrane protein pores supported in planar lipid bilayers or solid-state (SS) pores fabricated in thin metallic ...