Nanopore Sensors for Nucleic Acid Analysis. Nat. Nanotechnol. 2011; 6 :615–624.Venkatesan BM, Bashir R (2011) Nanopore sensors for nucleic acid analysis . Nature nanotechnology 6 : 615–624doi: 10.1038/NNANO. 2011.129Venkatesan BM, Bashir R. Nature Nanotechnology. 2011; 6 :615....
这意味着单链DNA(ssDNA)可以通过纳米孔,而双链DNA(dsDNA)不能。 ssDNA的过孔速度在典型的实验条件下非常快(预计小于1核苷酸/每微秒),这意味着小于100个离子数量在纳米孔中被正确检测。因此,不同核苷酸的出现微小的离子流变化很容易被热扰动(统计变化的电荷载流子的数目和孔中的核苷酸位置)所淹没。 大多数的纳米孔...
Nanopore analysis is an emerging technique that involves using a voltage to drive molecules through a nanoscale pore in a membrane between two electrolytes, and monitoring how the ionic current through the nanopore changes as single molecules pass through it. This approach allows charged polymers (inc...
Nanopore-based sensors have established themselves as a prominent tool for solution-based, single-molecule analysis of the key building blocks of life, including nucleic acids, proteins, glycans and a large pool of biomolecules that have an essential role in life and healthcare. The predominant mol...
Nanopores || Solid-State Nanopore Sensors for Nucleic Acid Analysis SM Iqbal,R Bashir 被引量: 0发表: 2011年 Solid-state nanopore sensors for nucleic acid analysis . Nanopore DNA analysis is an emerging technique that involves electrophoretically driving DNA molecules through a nano-scale pore in ...
M.; Bashir, R., Nanopore sensors for nucleic acid analysis. Nat Nanotechnol 2011, 6 (10), 615-24. 6. (a) Jung, Y.; Bayley, H.; Movileanu, L., Temperature-responsive protein pores. J Am Chem Soc 2006, 128 (47), 15332-40; (b) Heinz, C.; Engelhardt, H.; Niederweis, M.,...
Nanopore sensors for nucleic acid analysis success at deoxyribonucleic acid (DNA) sequencing, nanopore-based technologies offer one of the most promising approaches to single molecule detection and ... JJ Nakane,M Akeson,A Marziali - 《Journal of Physics Condensed Matter》 被引量: 224发表: 2003年...
Venkatesan BM, Bashir R (2011) Nanopore sensors for nucleic acid analysis. Nat Nanotechnol 6:615–624 Article Google Scholar Wanunu M, Dadosh T, Ray V, Jin J, McReynolds L, Drndic M (2010) Rapid electronic detection of probe-specific microRNAs using thin nanopore sensors. Nat Nanotechnol...
Nanopore sensors for nucleic acid analysis. Nat. Nanotechnol. 6, 615 (2011). Article CAS Google Scholar Dekker, C. Solid-state nanopores. Nat. Nanotechnol. 2, 209–215 (2007). Article CAS Google Scholar Derrington, I. M. et al. Nanopore DNA sequencing with MspA. Proc. Natl Acad. ...
Nanopore sensors for nucleic acid analysis. J Phys Condens Matter. 15, R1365–R1393 (2003). Article ADS CAS Google Scholar Healy, K. Nanopore-based single-molecule DNA analysis. Nanomedicine 2, 459–481 (2007). Article CAS Google Scholar Wang, J., Moore, N. E., Deng, Y. M., ...