MOG-2 is the worm homolog of spliceosomal protein U2A′. We found that MOG-2 is expressed in most nuclei of somatic and germ cells. In addition to its role in sex determination, mog-2 is required for meiosis. Moreover, MOG-2 binds to U2B″/RNP-3 in the absence of RNA. We also ...
Immunogen SNRNP200 fusion protein Ag20748 种属同源性预测 Host / Isotype Rabbit / IgG Class Recombinant Type Antibody Full Name small nuclear ribonucleoprotein 200kDa (U5) Synonyms HELIC2, EC:3.6.4.13, BRR2, ASCC3L1, Activating signal cointegrator 1 complex subunit 3-like 1 Calculated Molecular...
As the latter lacks a proline-rich tract, our data indicate that a GYF-domain can also engage in specific protein-protein interactions in a polyproline-independent manner. Interestingly, the U5-102K protein has been shown previously to play an essential role in tri-snRNP formation, binding ...
The interaction of 52K with a tri-snRNP bridging protein, coupled with its absence from the tri-snRNP, suggests it might function in tri-snRNP assembly. 机译:美国snRNP在依赖U2和U12的剪接中都起着至关重要的作用。在这里,我们表征了与人类US snRNP相关的52 kDa蛋白,称为U5-52K。蛋白质测序表明,...
As the latter lacks a proline-rich tract, our data indicate that a GYF-domain can also engage in specific protein–protein interactions in a polyproline-independent manner. Interestingly, the U5-102K protein has been shown previously to play an essential role in tri-snRNP formation, binding ...
Structural basis for the bifunctionality of the U5 snRNP 52K protein (CD2BP2). J. Mol. Biol. 369, 902-908.Nielsen, T. K., Liu, S., Lu¨hrmann, R. & Ficner, R. Structural basis for the bifunctionality of the U5 snRNP 52K protein (CD2BP2). J. Mol. Biol. 369, 902-908 (...
Crosslink- ing of the U5 snRNP-specific 116-kDa protein to RNA hairpins that block step 2 of splicing. RNA 3:1207-1219.Liu ZR, Laggerbauer B, Luhrmann R, Smith CW. Crosslinking of the U5 snRNP‑specific 116‑kDa protein to RNA hairpins that block step 2 of splicing. Rna 1997;...
A protein complex regulates RNA processing of intronic heterochromatin-containing genes in Arabidopsis In several eukaryotic organisms, heterochromatin (HC) in the introns of genes can regulate RNA processing, including polyadenylation, but the mechanism und... CG Duan,X Wang,L Zhang,... - 《Proc ...
PROTEINHELICASEBRR2The U5 small nuclear ribonucleoprotein particle (snRNP) helicase Brr2 disrupts the U4/U6 small nuclear RNA (snRNA) duplex and allows U6 snRNA to engage in an intricate RNA network at the active center of the spliceosome. Here, we present the structure of yeast Brr2 in ...
Gemin3 A Novel Dead Box Protein That Interacts with Smn, the Spinal Muscular Atrophy Gene Product, and Is a Component of Gems and SIP1 interact with the Sm core proteins of spliceosomal small nuclear ribonucleoproteins (snRNPs), and they play a critical role in snRNP assembly. In... Char...