A protein canyon in the FGF–FGF receptor dimer selects from an à la carte menu of heparan sulfate motifs 来自 Semantic Scholar 喜欢 0 阅读量: 36 作者:M Mohammadi,SK Olsen,R Goetz 摘要: Heparan sulfate (HS) is an essential and dynamic regulator of fibroblast growth factor (FGF) ...
Different canyons select different HS motifs The symmetric two-end model provides an intriguing solution to the problem of how HS selectivity is achieved in FGF signaling. Analysis of the contacts between heparin and the region of the canyon where the HBSs of each FGF and the two FGFR D2 doma...
Interanionic()OHO() Interactions: A Solid-State and Computational Study of the Ring and Chain Motifs It has been shown that hydrogen carbonates form RINGs, with the notable exception of NaHCO3, while only CHAINs are known for hydrogen oxalates. Hydrogen......
of beta-globin protein isotypes. To test specific predictions of this promoter competition model, a sensitive RNA/polymerase chain reaction assay has been used to investigate the effects of individual beta-globin promoter mutations on expression of the two linked genes in transiently transfected ...
One of the transit points on this old trade route, which runs from Portbou to Blanes, is the beautiful town... Cathedrals of Wine The road connecting the two large Cathedrals of Wine we visit in Terres de l’Ebre, the modernist bodegas of Gandesa... Arrival in Lleida In the Ivar...