From an analysis of current data on 16 protein structures with defined nucleotide-binding sites consensus motifs were determined for the peptide segments that form such nucleotide-binding sites. This was done by using the actual residues shown to contact ligands in the different protein structures, ...
Protein pattern and profile databases contain information on motifs found in sequences. Sequence motifs correspond to structural or functional features in proteins. So, the use of protein sequence patterns or profiles is a valuable tool in determining the function of proteins. InterPro InterPro is a...
For a proper understanding of protein structure and folding it is important to know if a polypeptide segment adopts a conformation inherent in the sequence or it depends on the context of its flanking secondary structures. Turns of various lengths have b
Arginine is an abundant residue in protein–protein interfaces. The importance of this residue relates to the versatility of its side chain in intermolecul... PB Crowley,A Golovin - 《Proteins Structure Function & Bioinformatics》 被引量: 537发表: 2005年 Cation–π/H-bond Stair Motifs at Prote...
Cell Commun Signal (2021) 19:60 https://doi.org/10.1186/s12964-021-00741-y REVIEW Open Access Types of nuclear localization signals and mechanisms of protein import into the nucleus Juane Lu1, Tao Wu1, Biao Zhang1, Suke Liu1, Wenjun Song1, Jianjun Qiao2,3,4*...
Nuclear localization signals (NLS) are generally short peptides that act as a signal fragment that mediates the transport of proteins from the cytoplasm into the nucleus. This NLS-dependent protein recognition, a process necessary for cargo proteins to pass the nuclear envelope through the nuclear ...
In other cases, proteins may be grouped due to the presence of additional sequence motifs not found across all Hox proteins (e.g. the UbdA motif, which is specific to protostome Ubx and Abd-A proteins). In the worst case, such clustering biases can lead to proteins being clustered ...
They are highly curated, often using a complex combination of computational algorithms and manual analysis and interpretation to derive new knowledge from the public record of science. Examples InterPro (protein families, motifs and domains)
Proteins are organized into four different levels of organization. The protein levels of organization are primary, secondary, tertiary and quaternary structures.Answer and Explanation: Become a member and unlock all Study Answers Start today. Try it now Create an account ...
While both enzymes synthesize the β(1,6)-GlcNAc linkage to α(1,6)-linked mannose on N-linked glycans the GnT-IX protein transfers GlcNAc to both the α1,3- mannose arm of the N-glycan as Scientific Reports | 6:26451 | DOI: 10.1038/srep26451 3 www.nature.com/scientific...