Structural motifs in protein cores and at protein–protein interfaces are differentprotein dockingprotein modelingprotein recognitionstructure predictionStructures of proteins and protein–protein complexes are determined by the same physical principles and thus share a number of similarities. At the same ...
Proteins tend to use recurrent structural motifs on all levels of organization. In this paper we first survey the topics of recurrent motifs on the local secondary structure level and on the global fold level. Then, we focus on the intermediate level which we call the short structural motifs....
Conserved sequencemotifs in and around the interacting residues are indicators for interaction sites. 3.2.6Secondary structure Interface residues can be classified according to the secondary structure they are part of, that is alpha-helices, beta-strands, turns, and loops. Less common are31...
Protein folds and domains, structural motifs and connectivity between secondary structure elements, helices and sheets
开学季特惠,9月3日-11月30日,专业版用户每周AI豆3倍膨胀,快来领取吧! 摘要原文 The high frequency of occurrence of the definite folding units in unrelated proteins and the fact that many small proteins are merely composed of the folding units indicate that these units can fold into unique structu...
H. & Grishin, N. V. MALIDUP: a database of manually constructed structure alignments for duplicated domain pairs. Proteins 70, 1162–1166 (2008). CAS PubMed Google Scholar Cheng, H., Kim, B. H. & Grishin, N. V. MALISAM: a database of structurally analogous motifs in proteins. ...
PRINTS is a protein ‘fingerprint’ database. Where other domain databases have entries of single motif representing a conserved domain, ‘fingerprint’ consist of multiple short motifs that represent a protein family or structural features (Attwood and Beck, 1994). Thus, ‘finge...
A Novel Algorithm for Enhanced Structural Motif Matching in Proteins As widely discussed in literature, spatial patterns of amino acids, so-called structural motifs, play an important role in protein function. The functional... F Kaiser,A Eisold,D Labudde - 《Journal of Computational Biology》 被...
On the other hand, functions of proteins are realized through their 3D structures. Specific local structures, called structural motifs, are considered as related to their functions. However, searching for common structural motifs in different proteins is much more difficult than for common sequence ...
Mitchell EM, Artymiuk PJ, Rice DW, Willett P: Use of techniques derived from graph theory to compare secondary structure motifs in proteins. J Mol Biol. 1990, 212 (1): 151-166. 10.1016/0022-2836(90)90312-A. Article CAS PubMed Google Scholar Levine M, Stuart D, Williams J: A metho...