Chemicals Facilitating Reprogramming: Targeting the SAM Binding Site to Identify Novel Methyltransferase Inhibitors 163 Jeong-Do Kim, Jong S. Rim, Robert B. Crochet, Yong-Hwan Lee, Jaroslaw Staszkiewicz, Ru Gao, and Kenneth J. EilertsenKim, J.-D.; Rim, J. S.; Crochet, R. B.; Lee, Y...
Structural Similarities between Sam and Atp Recognition Motifs and Detection of Atp Binding in a Sam Binding DNA Methyltransferase 来自 Semantic Scholar 喜欢 0 阅读量: 7 作者:S Sankar,P Preeti,K Ravikumar,A Kumar,Y Prasad,D Rao,H Savithri,N Chandra ...
The virus-encoded methyltransferase (MTase) plays an important role in viral replication. Here we show that ALSV MTase readily binds S-adenosyl-L-methionine (SAM) and S-adenosyl-L-homocysteine (SAH) but exhibits significantly lower affinities than canonical flaviviral MT...
DNA methyltransferase can increase plant stress resistance by modulating methylation levels of a few typical stress-resistance genes [32], [33]. In this study, association analysis identified genes associated with DMR that were involved in salt stress response and epigenetic regulation (Fig. 8B). ...
SETD8 is the methyltransferase responsible for monomethylation of lysine at position 20 of the N-terminus of histone H4 (H4K20). This activity has been implicated in both DNA damage and cell cycle progression. Existing biochemical assays have utilized truncated enzymes containing the SET domain of...