Identification of long non-protein coding RNAs in chicken skeletal muscle using next generation sequencing. Genomics, 2012, 99(5):292-298. [13]Peng ZY, Cheng YB, Tan BC, et al. Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcrip- tome. Nature ...
Skeletal Muscle, 2011, 1(1): 4. [27] DELLING U, TURECKOVA J, LIM H W, de WINDT L J, ROTWEIN P, MOLKENTIN J D. A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression. Molecular and Cellular Biology, 2000, 20(17): 6600...
nanoparticle-induced stress, we used the transcriptome sequencing (RNA-seq) technique to characterize the transcriptomes from adult zebrafish exposed to 10 mg/L carboxymethyl cellulose (CMC) stabilized FeS nanoparticles for 96 h, demonstrating striking differences in the gene expression profiles in ...
The ability to capture gene expression at the single cell resolution has propelled significant discoveries in the biomedical field over the last decade1,2. Specifically, single cell RNA-sequencing (scRNA-seq) provides novel insight into cellular heterogeneity across human tissues and facilitates the s...
Traversing down the lineages, OCAT uses the root cell as the point of reference in each local neighborhood to assign pseudotime to individual cells. We validate the performance of OCAT trajectory and pseudotime inference using the human skeletal muscle myoblast (HSMM) dataset [28]. The HSMM ...
rna-seq数据分析实用方法.pdf,RNA-seq Data Analysis A Practical Approach CHAPMAN HALL/CRC Mathematical and Computational Biology Series Aims and scope: This series aims to capture new developments and summarize what is known over the entire spectrum of mat
mesoderm. Previously, MESP1 was thought to be a heart-specific master regulator. “Several years ago,” notes Dr. Kyba, “we showed that MESP1 promotes the development of not only the heart, but also of other lineages, such as skeletal muscle and blood, which are different types of ...
(the dermomyotome). Cluster 2 was composed of skeletal muscle cells because of its specific expression ofFosandErg1, which are related to skeletal muscle cell differentiation. Cluster 3 included a population of muscle cells derived from the myotome that highly expressedTpm1andTpm2. Cluster 4 ...
One should bear in mind that the abundance of a transcript is not always predictive for the abundance of the corresponding protein and there are a number of studies which have investigated this in detail5. However, according to the central dogma in molecular biology, the information on a coding...
While the majority of cells contain a single nucleus, cell types such as trophoblasts, osteoclasts, and skeletal myofibers require multinucleation. One advantage of multinucleation can be the assignment of distinct functions to different nuclei, but comprehensive interrogation of transcriptional ...