CX-5461,RNAPolymeraseIinhibitor的详细介绍 Product Information Molecular Weight:513.61 Formula:C27H27N7O2S Purity:≥98% CAS#:1138549-36-6 Solubility:DMSO up to 2 mM Chemical Name:2-(4-methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][...
RNA polymerase I转录抑制剂(BMH-21) 英文名称: BMH-21 总访问: 128 国产/进口: 国产 半年访问: 2 产地/品牌: 百奥莱博 产品类别: 细胞生物学试剂 规格: 896705-16-1 最后更新: 2024-11-4 货号: M01669 CAS 号: 896705-16-1 参考报价: 立即询价 电话咨询 ...
BMH-21是一新型DNA嵌入剂(DNA intercalator),能结合rDNA并抑制RNA polymerase I的转录,不使组蛋白H2AX磷酸化。注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!CAS号:896705-16-1纯度:98.96%分子式:C21H20N4O2分子量:360.41结构式:储存条件:-20℃,有效期2年,溶入溶剂后-20℃请尽量在一个月内使用。相关...
RNA Polymerase I Inhibitor II, CX-5461会员价请登录市场价￥2445原厂型号 5.09265.0001 贝雷猫货号 RH156237 品牌 默克密理博/Millipore 单件重量 1kg 货期 45天 单位: 盒 包装: 盒 库存: 0 数量: 盒 + - 1盒起订,增量1盒 加入购物车立即购买 ...
RNA Polymerase I Inhibitor I 1PC X 10MG 中文名: 中文别名: CBNumber: CB95755586 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商3 RNA Polymerase I Inhibitor I 1PC X 10MG化学性质 安全信息 RNA Polymerase I Inhibitor I 1PC X 10MG性质、用途与生产工艺 ...
1. IntroductionFirst discovered as a bacterial phytotoxin that induced chlorosis in plants, TagetinTMRNA Polymerase Inhibitor is the only compound known to potently and selectivelyinhibit RNA polymerase III from a variety of eukaryotic organisms, including mammalian cells, Saccharomyces cerevisiae, ...
RNA polymerase inhibition plays an important role in the regulation of transcription in response to environmental changes and in the virus-host relationship. Here we present the high-resolution structures of two such RNAP-inhibitor complexes that provide the structural bases underlying RNAP inhibition ...
29. ARTSIMOVITCH I, CHU C, LYNCH A S, et al. A new class of bacterial RNA polymerase inhibitor affects nucleotide addition. Science. 2003;302(5645):650–654. [PubMed] [Google Scholar] 30. FENG Y, DEGEN D, WANG X, et al. Structural basis of transcription inhibition by CBR hydroxami...
RNase Inhibitor (40U/μl) 0.5 μl Hi T7 RNA Polymerase (100 U/μl) 0.5-1 μl DEPC-treated Water up to 20 μl 2. 37℃孵育 2-3h (通常 3h,即可获得>80 μg 的总产量)。 3. 反应完毕后,如需去除模板 DNA,加入 Dnase I(2U)37℃处理 15min。
Only one RNA polymerase was detected in E. coli, whereas multiple RNA polymerases have been found in mammalian systems. Widnell and Tata (1964, 1966) prepared Weiss’ aggregate enzyme from rat liver nuclei. Two different activities were detected. One—now RNA pol I—which was Mg2+-...