英文名称RNA Polymerase III Inhibitor 储存温度避光,-20°C储存 运输条件超低温冰袋运输 产品介绍 RNA聚合酶III抑制剂是一种细胞可渗透的吲哚并磺酰胺化合物,对RNA聚合酶III具有广谱抑制活性。RNA聚合酶III抑制剂可通过阻止RNA Pol III介导的tRNA转录来抑制酵母中的细胞生长。RNA聚合酶III抑制剂能够破坏病毒质和轮状...
RNA Polymerase III Inhibitor structure CAS No. 577784-91-9 Chemical Name: RNA Polymerase III Inhibitor Synonyms ML-60218, 10 mM in DMSO;RNA Polymerase III Inhibitor;RNA Polymerase III Inhibitor inhibitor;RNA Polymerase III Inhibitor - CAS 577784-91-9 - Calbiochem;InSolution RNA Polymerase III Inh...
产品名称:RNA Polymerase III Inhibitor 别名: N-[1-(3-(5-Chloro-3-methylbenzo[b]thiophen-2-yl-1-methyl-1H-pyrazol-5-yl)]-2-chlorobenzenesulfonamide CAS号: 577784-91-9 描述: RNA Polymerase III Inhibitor is a cell-permeable indazolo-sulfonamide compound that displays broad-spectrum inhibitory ...
RNA Polymerase III Inhibitor; RNA Polymerase III Inhibitor; Inhibidor de la ARN polimerasa III; RNA Polymerase III Inhibitor; RNA Polymerase III Inhibitor; 2-Chloro-N-[3-(5-chloro-3-methyl-1-benzothiophen-2-yl)-1-methyl-1H-pyrazol-5-yl]benzenesulfonamide; 2-chloro-N-[3-(5-chloro-3-meth...
产品名称:RNA POLYMERASE III INHIBITOR .0订购此产品 供应商:Merck 规格:10MG 目录价:3218 库存状态:三周左右 CAS编号:577784-91-9 应用范围:蛋白抑制 种属来源: 相关信息: RNA Polymerase III Inhibitor 产品信息 Form Off-white solid Primary Target activity against RNA Polymerase III ...
RNA polymerase III (Pol III) transcribes noncoding RNA, including transfer RNA (tRNA), and is commonly targeted during cancer and viral infection. We find that Herpes Simplex Virus-1 (HSV-1) stimulates tRNA expression 10-fold. Perturbation of host tRNA synthesis requires nuclear viral entry, ...
RNA polymerase III transcribes the genes encoding ribosomal 5S RNA, tRNAs, and a subset of other small RNAs. In Saccharomyces cerevisiae where the subunits have all been cloned and characterized by sequence, five subunits are shared by all three polymerase complexes. In addition, there i...
RNA polymerase (Pol) III transcribes essential non-coding RNAs, including the entire pool of transfer RNAs, the 5S ribosomal RNA and the U6 spliceosomal RNA, and is often deregulated in cancer cells. The initiation of gene transcription by Pol III requires the activity of the transcription facto...
RNA polymerase I (Pol I) specifically synthesizes ribosomal RNA. Pol I upregulation is linked to cancer, while mutations in the Pol I machinery lead to developmental disorders. Here we report the cryo-EM structure of elongating human Pol I at 2.7 Å re
An inhibitor of RNA polymerase II is described, wherein said inhibitor is selected a moiety which targets a protein selected from cyclin kinase 12 (CDK12) or its recruiting protein PAF1C. Particular examples of such inhibitors are polypeptides expressed by a gene selected from IldD, IldR, ...