RPL27 is predicted to mediateRNA binding protein and deregulate sumolyation. RPL37a issuggested to interact with CTNNB1, SCMH1 and ATBF1. It ispredicted to deregulate Wnt degradation pathway, inhibit尾-catenin migration and regulate homeotic transcription. Ourstudies on RPL41 did not allow ...
We concluded that a further four CRP genes (RpL17,RpL18A,RpL34bandRpL35A) are likely to beMinutegenes despite no Minute phenotype having been associated with the genomic region in which they reside. In each of these cases, the CRP gene lies in a gap in deletion coverage (Table4, Additio...
作者:TH Struck,F Fisse 摘要: Cryptic species are commonly understood as an artefact of morphologically oriented taxonomy. This view ignores the potential of evolutionary processess such as morphological stasis, parallelism and…" [more]年份: 2007 ...
Research2MeVt0oaa0lrul7y.mgoeld8, Issue 10, Article R216 Open Access The ribosomal protein genes and Minute loci of Drosophila melanogaster Steven J Marygold*, John Roote†, Gunter Reuter‡, Andrew Lambertsson§, Michael Ashburner†, Gillian H Millburn†, Paul M Harrison¶, Zhan ...
embedded deep in the core of the ribosomes either remain constant (the estimated fluctuations of their levels are within error bars) or their paralogs exchange (e.g., the levels of Rpl37a and Rpl37b are anticorrelated; see Figure 3E), indicating that each ribosome has a copy of Rpl37. ...
Notably, the aforementioned RPL8/RPL30 overexpression pattern strongly correlated with co-amplification of a region on 8q22–24 containing genes encoding these two RPs as well as the Myc onco- protein and PVT1, a long-non-coding RNA (lncRNA) with oncogenic properties [36, 37]. Similarly, ...
RACK1 was originally identified as a PKC receptor4, and later as a 40S ribosomal protein2. RACK1 has been suggested to be involved in more than 200 interactions5, without ever demonstrating if RACK1 binds its interactors on the ribosome, or independently of. More recently, an high throughput...
Differential expression of a subset of ribosomal protein genes in cell lines derived from human nasopharyngeal epitheliumdifferential expressionhuman cell linesnasopharyngeal epitheliumNPCRPLRPL27RPL37aRPL41Extraribosomal functions of human ribosomal proteins (RPs) include the regulation of cellular growth and ...
In aging cells, the overall protein synthesis decreases with an increased rate of incorporation of wrong amino acids into the newly synthesised proteins. The deletion of certain proteins (RPL3, RPL6b, RPL10, RPS6, and RPS18) of the ribosome in yeast showed an increase in lifespan, similar ...