The protein contains a typical Cys2Cys2 zinc finger motif, which may be involved in protein-RNA interaction.doi:10.1016/0167-4781(92)90058-8Seikichi TokuTatsuo TanakaBiochim Biophys ActaThe primary structure of chicken ribosomal protein L37a. Toku S and Tanaka T. Biochimica et Biophysica Acta ...
The ribosomal protein P0 is part of a group of acidic proteins that form a stalk-like structure in the largest ribosome subunit, playing a fundamental role in regulating the translational activity of ribosomes and helping adjust an organism's metabolism to different environmental conditions (Rodrígue...
(2008) Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans. Cell Death Differ 15: 841–848. [44] Llanos S, Serrano M (2010) Depletion of ribosomal protein L37 occurs in response to DNA damage and activates p53 through the L11...
Structure of the human 80 S ribosome. Nature 2015; 520: 640–645. CAS PubMed Google Scholar Brar GA, Weissman JS . Ribosome profiling reveals the what, when, where and how of protein synthesis. Nat Rev Mol Cell Biol 2015; 16: 651–664. CAS PubMed PubMed Central Google Scholar ...
In bacteria, stable RNA structures that sequester ribosome-binding sites (RBS) impair translation initiation, and thus protein output. In some cases, ribosome standby can overcome inhibition by structure: 30S subunits bind sequence-nonspecifically to a single-stranded region and, on breathing of the...
Ribosome biogenesis and protein synthesis are fundamental rate-limiting steps for cell growth and proliferation. The ribosomal proteins (RPs), comprising the structural parts of the ribosome, are essential for ribosome assembly and function. In addition
This review article explores the intricate role, and regulation of ribosomal protein in response to stress, particularly emphasizing their pivotal role to
Furthermore, as scaffold proteins, RPs can not only sustain the structure of ribosomes but also regulate the spatial conformation, which plays a significant role in protein synthesis [1]. The primary site for protein synthesis is the peptidyl transferase center (PTC) within the large subunit of...
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