Ribosomal proteins located at the peptidyl transferase center, specifically ribosomal protein L26 (Villarreal and Lee, 1998; Marzouki et al., 1990), can regulate initiation of translation via interaction with elongation factor-2 (Nygard et al., 1987). Lee and Horowitz (1992) suggested that L26...
a Structure of the Escherichia coli 30S ribosomal subunit (PDB id: 4ADV). 16S ribosomal RNA is shown as blue ribbon. bS21 ribosomal protein is highlighted in pink. b Alignment of the ribosomal protein bS21 encoded by pelagiphage HTVC008M with homologs from representatives of distinct ...
Using Drosophila, we discovered that a bZip-domain protein, Xrp1, becomes elevated in Rp mutant cells. Xrp1 reduces translation and growth, delays development, is responsible for gene expression changes, and causes the cell competition of Rp heterozygous cells from genetic mosaics. Without Xrp1, ...
Virus-encoded ribosomal protein bS21.aStructure of theEscherichia coli30S ribosomal subunit (PDB id: 4ADV). 16S ribosomal RNA is shown as blue ribbon. bS21 ribosomal protein is highlighted in pink.bAlignment of the ribosomal protein bS21 encoded by pelagiphage HTVC008M with homologs from repr...
Research2MeVt0oaa0lrul7y.mgoeld8, Issue 10, Article R216 Open Access The ribosomal protein genes and Minute loci of Drosophila melanogaster Steven J Marygold*, John Roote†, Gunter Reuter‡, Andrew Lambertsson§, Michael Ashburner†, Gillian H Millburn†, Paul M Harrison¶, Zhan ...
brucei homologs, TcP37 is an efficient 5S rRNA binding protein in vitro. This binding is specific since polyadenylated RNAs do not associate with TcP37. In addition, we demonstrated that TcP37 also associates both in vivo and in vitro with the L5 ribosomal protein and is part of a complex...
a Structure of the Escherichia coli 30S ribosomal subunit (PDB id: 4ADV). 16S ribosomal RNA is shown as blue ribbon. bS21 ribosomal protein is highlighted in pink. b Alignment of the ribosomal protein bS21 encoded by pelagiphage HTVC008M with homologs from representatives of distinct ...
ZC3H41 was found associated with an essential protein, which we named Z41AP, forming a stable heterodimer, and also with proteins of the poly(A)-binding protein 1 complex. The identification of mRNAs associated with the ZC3H41/Z41AP complex revealed that it is...
Protein A beads (Pierce) were equilibrated with the lysis buffer and 50 μl of a 50% suspension was added to the immunoprecipitate and mixed on the Nutator at 4°C for 1 hour. The beads were collected by spinning at 10 k rpm in an Eppendorf microfuge for 15 seconds, washed twice in...
(Fig.2a, Supplementary Fig.2c). A search for structural homologs to Tsr2-N using the DALI protein structure comparison web server (http://ekhidna2.biocenter.helsinki.fi/dali/) indicated a modest similarity (Z-score of 7.5 and an rmsd of 2.7 Å for only five α-helices excluding α...