We identified three major strands of delta scholarship which are briefly discussed below in order to set the scene for the systems research that we focus on in the remainder of the article. The first strand of delta research looks at mitigating the impact of nature on delta societies through ...
The biological mechanism underlying this negative effect on reproductive potential is potentially related to DNA damage in the primordial oocytes that can occur in the form of both single- and double-strand breaks (DSBs) [78]. DSBs are the most deleterious damage that can result in failed rearran...
Despite progress, breast cancer remains the most feared disease among women. In the USA alone, the incidence is now almost 300,000 new cancers per year, a
In many countries, hormone receptor status assessment of ductal carcinoma in situ (DCIS) is routinely performed, as hormone receptor-positive DCIS patients are eligible for adjuvant anti-hormonal treatment, aiming to reduce the ipsilateral and contralate
[6]. We did not find any large cohort studies investigating FC associated with affective loss and have reviewed smaller studies to gather information on this topic. fMRI studies on bereavement of a first-degree relative [76,77] or spouse [78], the loss of an unborn child [79] or only ...
(RBD1 is shown here) are formed by beta-strand parts and alpha helical domains. The color gradient follows the structure from blue (N-terminal) to red (C-terminal). (C) Protein expression profile for different tissues based on the dataset of the human protein atlas webpage [24,25,26,...
mutant status if using the p53 positive samples. Thus, such information plus only a limited area (exons 4–8) of p53 gene mutation being tested by the single strand conformation polymorphism (SSCP) analysis in their study blocked us to obtain a clear conclusion for this case....
by the need to use a tracer that do not impair T-cell functionality or do not present biological effects. All in all, the field of T-cell tracking and imaging is an intriguing and hot topic for researchers in the era of immunotherapy. ...
Conventional pre-genomics breeding methodologies have significantly improved crop yields since the mid-twentieth century. Genomics provides breeders with advanced tools for whole-genome study, enabling a direct genotype–phenotype analysis. This shift ha
but also genetic and epigenetic aberrations in spermatozoa. Both animal and human studies have highlighted the occurrence of sperm DNA-strand breaks (fragmentation), genome instability, genetic mutations, and the presence of aneuploids in the germline of animals and men exposed to tobacco smoke. The...