29 Cuzner ML, Gveric D, Strand C, Loughlin AJ, Paemen L, Opdenakker G, et al. The expression of tissue-type plasminogen activator, matrix metalloproteases and endogenous inhibitors in the central nervous system in multiple sclerosis: comparison of stages in lesion evolution. J Neuropathol Exp...
An A-base was added to the blunt ends of each strand to prepare them for ligation to the indexed adapters. Each adapter contained a T-base overhang to ligate the adapter to the A-tailed fragmented DNA. Single- or dual-index adapters were ligated to the fragments and size selection was ...
First- and second-strand cDNA synthesis, labelling and hybridisation to Affymetrix Human Gene 1.0ST arrays were performed according to the standard Affymetrix protocol. Affymetrix data were extracted, normalised and summarised using the robust multi-average method implemented in the Affymetrix Expression ...
Another autoimmune disorder is systemic sclerosis (SS). SS does not affect the morphology of MSCs obtained from adipose tissue. MSCs express the same surface antigens, but it was noticed that the expression of CD146, which is considered to be a marker of multipotency, is lower. However, no...
68 Consistently, in embryonic stem cells (ESC) MYBL2 depletion leads to stalling of replication forks, disorganization of the replication program and an increase in double-strand breaks.41 It has been shown that these effects are, at least in part, mediated by deregulation of MYC and FOXM1 ...
Mail BagSeveral letters to the editor are presented in response to articles in previous issues including articles concerning actress Sandra Bullock, reality television star Richard Hatch, and news anchor Thomas Roberts.Rooney, BrendaDanks, EmilyMiller, Liz...
89病灶的结构和染色缺失的模式是重要的考量。SSADs边缘有锯齿(LS的腺瘤几乎没有),可能说明MLH1和PMS2联合丧失(不是MSH2和/或MSH6)。而表达丧失一般被认为是晚期现象,通常是对肿瘤侵袭的应答。(然而表表达丧失在LS腺瘤中很常见,常伴有轻度不典型增生。)
demonstrated that cell-free nucleic acids and cell-free chromatin particles can enter healthy cells, integrate into their genomes and elicit DNA double-strand breaks and apoptotic responses [28]. Because of genomic integration, the NF-κB pathway is activated leading to the induction of a systemic...
MBS651929 Tissue cDNA, First Strand Adult Normal, Brain, Hippocampus, BioGenomics cDNA 10 rxn mybiosource RE010212 AOPI染料 5ml countstar CO010101 细胞计数板(5孔) 50个/盒 countstar GS500 Giemsa stain, modified (Sigma-Aldrich) 500 ML Sigma 69-201 Factor IX Depleted Plasma 10 x 1 mL r2dia...
MBS651929 Tissue cDNA, First Strand Adult Normal, Brain, Hippocampus, BioGenomics cDNA 10 rxn mybiosource RE010212 AOPI染料 5ml countstar CO010101 细胞计数板(5孔) 50个/盒 countstar GS500 Giemsa stain, modified (Sigma-Aldrich) 500 ML Sigma 69-201 Factor IX Depleted Plasma 10 x 1 mL r2dia...