British Journal of Cancer volume 129, pages 1306–1313 (2023)Cite this article 4182 Accesses 4 Citations 4 Altmetric Metrics details Abstract Background Tobacco smoking is suggested as a risk factor for colorectal cancer (CRC), but the complex relationship and the potential pathway are not fully...
Article PubMed Google Scholar Ceccaldi R, Rondinelli B, D’Andrea AD. Repair Pathway Choices and Consequences at the Double-Strand Break. Trends Cell Biol. 2016;26(1):52–64. Article CAS PubMed Google Scholar Lin KK, Harrell MI, Oza AM, Oaknin A, Ray-Coquard I, Tinker AV, et ...
The current debate about AI focuses on potential risks such as algorithmic bias and discrimination, loss of specific jobs, and other issues. Despite these dystopian scenarios, some scientists/physicians are focusing on the potential rewards of implementing AI. Some have argued that AI can solve some...
About this article Cite this article Jamison, D.A., Anand Narayanan, S., Trovão, N.S.et al.A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection.Eur J Hum Genet30, 889–898 (2022). https://doi.org/10.1038/s41431-022-01108-8...
Long non-coding RNAs (lncRNAs) have gained increasing attention as they exhibit highly tissue- and cell-type specific expression patterns. LncRNAs are highly expressed in the central nervous system and their roles in the brain have been studied intensive
Approximately 100 million confirmed infections and 20,000 deaths are caused by Dengue virus (DENV) outbreaks annually. Global warming and rapid dispersal have resulted in DENV epidemics in formally non-endemic regions. Currently no consistently effective
Virtual compound libraries are increasingly being used in computer-assisted drug discovery applications and have led to numerous successful cases. This paper aims to examine the fundamental concepts of library design and describe how to enumerate virtual
Familial Hypercholesterolaemia is an autosomal, dominant genetic disorder that leads to elevated blood cholesterol and a dramatically increased risk of atherosclerosis. It is perceived as a rare condition. However it affects 1 in 250 of the population gl
the uneven methylation status of CpG between the original and newly synthesised strand at the 3′ end may reflect the length of the jagged end. By utilising the publicly available cfDNA and gDNA WGBS data, Jiang et al. showed the proof-of-concept results of the genome-wide presence of jagge...
Cells are minimal functional units in biological phenomena, and therefore single-cell analysis is needed to understand the molecular behavior leading to cellular function in organisms. In addition, omics analysis technology can be used to identify essent