The third strand of delta research focussing on livelihoods of delta communities is more cautious about the sustainability of delta living. It considers human society adaptable and inventive (Musa et al., 2016; Vogt et al., 2016), but emphasises the vulnerability of resource-poor delta inhabitants...
Search-and-replace genome editing without double-strand breaks or donor DNA. Nature. 2019;576(7785):149–57. Article CAS PubMed PubMed Central Google Scholar Baba T, Momen M, Campbell MT, Walia H, Morota G. Multi-trait random regression models increase genomic prediction accuracy for a ...
Strand SH, Rivero-Gutiérrez B, Houlahan KE, Seoane JA, King LM, Risom T, et al. Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: analysis of TBCRC 038 and RAHBT cohorts. Cancer Cell. 2022;40:1521-1536.e7. Article PubMed PubMed Central CAS ...
The biological mechanism underlying this negative effect on reproductive potential is potentially related to DNA damage in the primordial oocytes that can occur in the form of both single- and double-strand breaks (DSBs) [78]. DSBs are the most deleterious damage that can result in failed rearran...
The human brain is well known to exhibit plasticity, an intrinsic ability to reorganise its structure and function throughout the lifespan [4]. This allows the brain to adapt to changes in the external environment or internal milieu. With respect to external environmental influences, like the ex...
(RBD1 is shown here) are formed by beta-strand parts and alpha helical domains. The color gradient follows the structure from blue (N-terminal) to red (C-terminal). (C) Protein expression profile for different tissues based on the dataset of the human protein atlas webpage [24,25,26,...
TCR-transduced TCMcells were exposed to different activities of [89Zr]Zr-Df-aTCRmu-F(ab′)2up to 37 MBq showing that the tracer leads to double-strand breaks (DSBs) and cell death only at higher activities not clinically meaningful. Furthermore, the possible damage of T-cells, once ...
[47]Raver, C. C., & Knitzer, J. (2002). Ready to Enter: What Research Tells Policy Makers about Strategies to Promote Social and Emotional School Readiness among Threeand Four-Year-Olds. Washington DC: National Center for Children in Poverty. ...
Yala A, Mikhael PG, Strand F, Lin G, Satuluru S, Kim T et al (2022) Multi-institutional validation of a mammography-based breast cancer risk model. J Clin Oncol Off J Am Soc Clin Oncol 40(16):1732–1740 Google Scholar Shieh Y, Eklund M, Madlensky L, Sawyer SD, Thompson CK, Sto...
but also genetic and epigenetic aberrations in spermatozoa. Both animal and human studies have highlighted the occurrence of sperm DNA-strand breaks (fragmentation), genome instability, genetic mutations, and the presence of aneuploids in the germline of animals and men exposed to tobacco smoke. The...