British Journal of Cancer volume 129, pages 1306–1313 (2023)Cite this article 4182 Accesses 4 Citations 4 Altmetric Metrics details Abstract Background Tobacco smoking is suggested as a risk factor for colorectal cancer (CRC), but the complex relationship and the potential pathway are not fully...
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About this article Cite this article Jamison, D.A., Anand Narayanan, S., Trovão, N.S.et al.A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection.Eur J Hum Genet30, 889–898 (2022). https://doi.org/10.1038/s41431-022-01108-8...
When PARP1 is deficient, SSB cannot be repaired [16]. Through the process of DNA replication, SSB converts into a double-strand breaks (DSB), and the DSB repair system is then required. Three mechanisms exist to repair DSB: non-homologous end joining (NHEJ), microhomology-mediated end join...
[41,42]. It is worth noting that the accumulation of this mucus is related to the decrease of FVC. Some studies have shown that SIgA can bind to the surface of A549 cells. A549 is usually used as a cell line with AT2 cell phenotype in vitro experiments, which can promote the ...
Long non-coding RNAs (lncRNAs) have gained increasing attention as they exhibit highly tissue- and cell-type specific expression patterns. LncRNAs are highly expressed in the central nervous system and their roles in the brain have been studied intensive
2 adding AI applications to an already fragmented healthcare system will not create sustainable healthcare changes; 3. most healthcare organizations lack the infrastructure required to collect the data to optimally train algorithms to (a) “fit” the local population and/or the local medical practic...
Lymph nodes play a pivotal role in tumor progression as key components of the lymphatic system. However, the unique physiological structure of lymph nodes has traditionally constrained the drug delivery efficiency. Excitingly, nanomedicines have shown tr
We have previously developed an OI approach for early detection of oral cancer that targets the DNA repair enzyme PARP1. PARP1 plays a central role in initiating the DNA damage repair response (DDR), especially for single-strand breaks [22,23]. PARP1 expression is strongly increased in many...
This article has been updatedAbstract Advanced gastric cancer is often accompanied by metastasis to the peritoneum, resulting in a high mortality rate. Mechanisms involved in gastric cancer metastasis have not been fully clarified because metastasis involves multiple steps and requires a combination of ...