In the present review, the mechanisms through which protein SUMOylation is regulated are discussed, with particular emphasis on the impact of signalling pathways. A major point of regulation of the SUMO pathway is through targeting the E3 ligases, and a number of different ways to achieve this ...
1998a . The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival. Biochem J 333: 291 ... ET Maizels,C Joshua,JCR Jones,... - 《Endocrinology》 被引量: 336发表: 1998年 A late adenovirus factor induces eIF-4E dephosphorylati...
Signalling pathways involved in nicotine regulation of apoptosis of human lung cancer cells. Carcinogenesis 1998; 19:551–6.Heusch, WL, Maneckjee, R... W.,Heusch - 《Carcinogenesis》 被引量: 336发表: 1998年 Nicotine Inactivation of the Proapoptotic Function of Bax through Phosphorylation Nicotine...
However, the core molecular pathways and effector mechanisms that regulate sleep duration in mammals remain unclear. Here, we characterize a major signalling pathway for the transcriptional regulation of sleep in mice using adeno-associated virus-mediated somatic genetics analysis4. Chimeric knockout of ...
Linear ubiquitination is a critical regulator of inflammatory signaling pathways. However, linearly ubiquitinated substrates and the biological significance of linear ubiquitination is incompletely understood. Here, we show that STAT1 has linear ubiquiti
New insights into extracellular and post- translational regulation of TGF-β family signalling pathways. J Biochem 154... S Osamu,SJ Newfeld - 《Journal of Biochemistry》 被引量: 26发表: 2013年 New insights into extracellular and post-translational regulation of TGF- family signalling pathways ...
Melanoma-intrinsic beta-catenin signalling prevents anti-tumour immunity. Nature. 2015;523:231–5. Article CAS PubMed Google Scholar Pai SG, Carneiro BA, Mota JM, Costa R, Leite CA, Barroso-Sousa R, et al. Wnt/beta-catenin pathway: modulating anticancer immune response. J Hematol Oncol. ...
Signal transduction pathways of gonadotropin receptors: Origin, divergence, and regulation 来自 掌桥科研 喜欢 0 阅读量: 20 作者: RL Gilchrist 摘要: Gonadotropin hormones, follicle stimulating hormone (FSH), luteinizing hormone (LH), chorionic gonadotropin (hCG), and thyroid stimulating hormone (TSH) ...
To study the resistance pattern in different breeds of chicken, a comprehensive understanding of TLR4 signalling pathways is required. We investigated the TLR-4 pathway regulated gene expressions in PBMCs of chicken breeds of Broiler (Cobb), Aseel, Dahlem Red and Ghagus upon LPS treatment using ...
The signalling pathways controlling both the evolution and development of language in the human brain remain unknown. So far, the transcription factor FOXP2 (forkhead box P2) is the only gene implicated in Mendelian forms of human speech and language dysfunction. It has been proposed that the ami...