Pathway pathology: how to identify signaling pathways in mouse models of human breast cancercirculating cellsChromogranin A transcriptsneuroendocrine carcinomaHigh grade lung neuroendocrine carcinomas, like small and large cell neuroendocrine carcinomas, pose therapeutic problems. Most initially respond to ...
The gold standard to determine ID is to determine iron content of the bone marrow. However, this is not feasible in routine clinical practice [17]. Therefore, different non-invasive biochemical markers are widely used to determine ID. Types of biochemical markers Serum iron In case of ID, ser...
Root dynamic growth strategies in response to salinity 2022, Plant Cell and Environment Function of membrane domains in rho-of-plant signaling 2021, Plant Physiology The value of asymmetry: How polarity proteins determine plant growth and morphology 2020, Journal of Experimental Botany View all citing...
Aim 2. What inter-tissue stress signaling pathways are activated by 5-HT in responsive cells? Public Health Relevance 'Proteinopathies,' diseases of protein misfolding and aggregation, are debilitating age-related diseases such as ALS, Alzheimer's, Parkinson's and Huntington's Diseases, for ...
Can we one day use parts to create a whole?; (B) The main reason why we would like to control living systems is to control how one cell behaves and in this way, determine what it does e.g. differentiation. The tools to achieve such fates are only beginning to come of ...
This helps it be difficult to determine whether there’s enough of the main element ingredients to work. I noticed no unwanted effects but I would advise visitors to take the product either very first thing each morning or midday, and no afterwards than 4 pm in the afternoon if you want ...
Accordingly, the ability to rationally manipulate these interactions will represent a key enabling technology for understanding the properties of natural cellular networks, for building new biological responses into cells, and even as a starting point for therapeutic intervention in certain human diseases....
J. Notch-regulated ankyrin-repeat protein inhibits Notch1 signaling: multiple Notch1 signaling pathways involved in T cell development. J. Immunol. 170, 5834–5841 (2003). Article CAS PubMed Google Scholar Hosoya, T. et al. GATA-3 is required for early T lineage progenitor development. J....
Both cancer and fibrosis are diseases involving dysregulation of cell signaling pathways resulting in an altered cellular microenvironment which ultimately leads to progression of the condition. The two disease entities share common molecular pathophysiology and recent research has illuminated the how each pr...
ROCKi also inhibited the transition to the luminal airway progenitor phenotype, by repressing signaling pathways (Notch 1 signaling, Notch 1 receptor, Notch ICD, DLL-1), cell–cell interaction molecules (claudin10,11 and occludin) and protease genes (MMP 2,9,14 and 28) typical for the ...