蛋白质-蛋白质相互作用(protein-protein interaction,PPI)是指两个或两个以上的蛋白质分子通过非共价键形成蛋白质复合体(protein complex)的过程。研究蛋白之间的相互作用网络,有助于挖掘核心的调控基因,目前已经有很多的蛋白质相互作用的数据库,在这里,...
Protein-Protein interaction network 夏夏 生物信息学6 人赞同了该文章 实验得到数据后,要验证结果并提高总体交互连接的质量,有很多方法用于分析PPI datasets 1:评估数据集的质量 计算数据集的false discovery rate (FDR )。主要策略:通过多种方法验证检测到的interaction,与文献中获取的interaction作比较。 2:计算方法...
Synonyms Protein interaction network ; Protein physical interaction network Definition A protein-protein interaction (PPI) network is a network or graph representation of physical interactions between protein pairs in an organism. In the network, each node/vertex represents a protein and each edge/link...
Protein‐protein interaction networkSystems biologyMapping the intricate networks of cellular proteins in the human brain has the potential to address unsolved questions in molecular neuroscience, including the molecular basis of cognition, synaptic plasticity, long term potentiation, learning and memory. ...
网络释义 1. 蛋白质互作网络 互作网络,interaction... ... ) protein interaction network 蛋白质互作网络 ) interaction network 互作网络 ... www.dictall.com|基于1 个网页 例句 释义: 全部,蛋白质互作网络 更多例句筛选 1. Most potent drug target can be identifying among large number of non-homologous...
A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology Multiple computational methods have been developed to understand how mutations drive tumourigenesis, but their insights are largely non-overlapping. Here, the authors introduce NetFlow3D, a framewo...
点击interaction之后,可以看到这些基因与BRCA2这个基因之间的交互关系,或者可以说是影响力有多少 之后我们将这个网络导入到cytoscape这软件中,这个软件专门是为了呈现某个交互网络的信息和图片的软件 这里导入到cytoscape有两个办法,一个是将上面的network下载下来然后直接导入到cytoscape中,另一个就是我们可以在cytoscape中直...
Protein-proteininteraction networks FunctionalGenomics RolandKrause roland.krause@molgen.mpg.de 1 Protein-Proteininteractions 1. Experimentalmethods(today) 2. Modulesandcomplexes 3. Networkevolution? 2 Protein-proteininteractions Experimentalapproaches ...
Protein-Protein Interaction (PPI) Networks Network Community Structure Community Detection Network Growing Biological Networks Biological Networks Modeling biological systems Genetic networks Gene association and expression Protein networks Protein structure and interactions ...
Based on the graph theory, a protein network is a graph where the nodes are proteins and the edges are either functional (e.g., pathway information from metabolic or signaling databases) or physical interactions (e.g., from the IMEx consortium for protein–protein interaction information (Orchar...