Protein-protein interactions are correlated with a proposed potential of mean force equal to the free energy to desolvate the protein surface that is made inaccessible to the solvent due to the protein-protein interaction. This energy is calculated from the surface free energy of the protein that...
The goal of this study was to relate conformational changes in the N-terminal domain of chicken troponin I (TnI) to Ca 2+ activation of the actin-myosin interaction. The two cysteine residues in this region (Cys48 and Cys64) were labeled with two sulfhydryl-reactive pyrene-...
The interaction of proteins thus prepared was visualized using a single-molecule imaging technique. As a demonstration of this method, a motor protein, kinesin, was labeled with Cy5-puro at an efficiency of about 90%, and the processive movement of kinesin along microtubules was observed by ...
Analysis of predicted interaction networks in context of expression correlation in various conditions reveals the dynamic changes associated with a number of biological processes. Full-size image (31K) View Within Article Figure 1 The performance of machine learning methods on gold standard data using ...
protein–protein interaction (PPI) prediction ‐ major role in biological processessupport vector machines (SVM) ‐ supervised learning method for classification, function approximation, signal processing and regression analysisPPIs prediction, based on whole genome analysis...
protein interaction prediction based on multidomain pairsSabir MA, Sosulski FW, Finlayson AJ.Chen, LuonanOsaka Sangyo University, JapanWang, Rui‐ShengRenmin University of China, ChinaZhang, Xiang‐SunChinese Academy of Science, ChinaJohn Wiley & Sons, Inc....
The overall model architectures for both the prediction of interaction sites (Figure 2A) and protein interaction prediction (Figure 2B) are very similar, as in both cases, the input consists of proteins and the output consists of a binary value. In particular, the initial processing sequence of...
The genes that do not participate in protein–protein interaction are eliminated in the first step. Furthermore, these genes do not create any proteins and do not participate in cellular division. In the second step, PCC is computed for every gene, and if a negative value is found, the ...
(CqMV1), in someChenopodium quinoaaccessions. In this study, we analyzed the mitochondrial proteome from leaves of quinoa, infected and not infected by CqMV1. Furthermore, by protein–protein interaction and co-expression network models, we provided a system perspective of how CqMV1 affects ...
of pollinated pistils and in the comparison of self-compatible and self-incompatible pollinations, respectively. On the other hand, as observed in the Venn diagram (Figure 2), the largest group of DEPs was obtained when comparing the compatible interaction with the incompatible interaction. ...