due to genetic changes caused by failed DNA repair, cancer cells do not always do so. Instead, the cancer cell splits up, creating many newcells, which can potentially develop into a cancer tumour.
Cancer cells divide very rapidly and the proteins that perform this task and keep the cells growing rely upon chaperones to fold correctly. By blocking the machinery that folds the proteins into the right shape, it should be possible to stop the cancer cells from growing. And because cancer ce...
Prostate Cancer Diagnosis, Treatment Could Be Improved By Protein That Suppresses Androgen ReceptorsToni Baker
The aberrant activation of these enzymes can lead to the uncontrolled cell growth that is typical of cancer, and distinct phosphorylation and de-phosphorylation mechanisms have evolved to control the activity of protein kinases through a reversible alteration in enzyme conformation. The structural ...
Treatment strategy of solid tumors requires continuous development. Here the authors develop a Macrophage Drug Conjugate (MDC) platform by loading ferritin-drug complexes to macrophages. MDC transfers the ferritin to cancer cells via ‘TRAnsfer of Iron binding protein’ (TRAIN) process and reduces tumo...
regulating the motility of tumor cells to prevent tumor cells from spreading and improve patient survival has also become one of the focuses of cancer treatment. Tspan1 regulates MMP2 expression through PLCγ and inhibits migration and invasion of pancreatic cancer cells [20]. In lung cancer, Tsp...
Prevention or treatment: the benefits of Trichomonas vaginalis vaccine. J Infect Public Health. 2010;3:47–53. Article PubMed Google Scholar Heidary F, et al. Design of a new multi-epitope peptide vaccine for non-small cell Lung cancer via vaccinology methods: an in silico study. Mol Biol...
A rare variant of a protein present in nearly all human cells may hold the key to improving the effectiveness of breast cancer treatment, according to University of Manchester research funded by Bre…
Ovarian cancer is the fifth leading cause of cancer-related deaths among women, and the second one among gynecologic cancers [1]. The standard regimen for advanced epithelial carcinoma (EOC) is debulking surgery following cis-platinum/taxane-based chemotherapy. During treatment, resistance often develo...
New research from the University of Liverpool has identified the role of a specific protein in the human body that can help prevent the survival and spread of eye cancer, by initiating cancer 'cell-suicide'.