Cancer CellsDNA DamageCell DeathsA recently discovered protein plays a role in preventing cell death when DNA damage occurs. Cells with DNA damage are able to remain alive, furthering the development of cancer. Normally, when the DNA in cells becomes damaged, a pro-sur...
Researchers in Taiwan report for the first time that blocking a key energy-supplying protein kills cancer cells. The finding, described as the first to test possible medical uses of so-called ATP-synthase inhibitors, may lead to new and more effective anti-cancer medications, according to their ...
Ph.D., showed that high expression of PEA-15 inhibits the growth of ovarian cancer cells by killing cells via autophagy, or self-cannibalization, rather than by apoptosis. Removing PEA-15 from ovarian cancer cells led to a 115 percent increase in the number of cells compared with a control ...
Nutrient Autophagy Factor 1 (NAF-1; NAF-144-67), selectively permeates and kills human metastatic epithelial breast cancer cells (MDA-MB-231), but not control epithelial cells. As cancer cells
cancer cells, loss of function ofFBXW7results in an elevated expression of c-Myc. Activation of c-Myc results in the upregulation of NSUN2 that is essential for cell proliferation. Owing to a synthetic lethality betweenFBXW7andNSUN2, targetingNSUN2kills cancer cells, while leaving normal ...
Recombinant TNF-B1 (Fv) fusion protein selectively kills LEY-antigen expressing TNF-α sensitive human cancer cells : Uwe Scherf, Itai Benhar, Keito O. Webber, Ira Pastan, Ulrich Brinkmann, Laboratory of Molecular Biology, DBS, National Cancer Institute, National Institutes of Health, Bethesda,...
(2017) PSMA-homing dsRNA chimeric protein vector kills prostate cancer cells and evokes anti-tumor immunity. Oncotarget. 2017;8(15):24046–62. https://doi.org/10.18632/oncotarget.15733. Article PubMed PubMed Central Google Scholar Fish A, Lebendiker M, Nechushtai R, Livnah O. ...
Parasporin-1Ab, a novel Bacillus thuringiensis cytotoxin preferentially active on human cancer cells in vitro The non-insecticidal Bacillus thuringiensis strain B0195 produces parasporin (PS) whose cytocidal activity is preferential for human cancer cells. This stu... A Uemori,A Ohgushi,K Yasutake,...
The adenovirus protein E4orf4 kills cancer cells but not normal primary cells. The possibility of developing a drug that mimics the killing by E4orf4 for c... MJ Miron - McGill University (Canada). 被引量: 0发表: 2007年 The role of adenovirus E4orf4 protein in viral replication and ...
A compound found in green tea may trigger a cycle that kills oral cancer cells while leaving healthy cells alone, according to Penn State food scientists. The research could lead to treatments for oral cancer, as well as other types of cancer. ...