et al. Personalized liposome–protein corona in the blood of breast, gastric and pancreatic cancer patients. Int. J. Biochem. Cell Biol. 75, 180–187 (2016). Article CAS Google Scholar Pink, M., Verma, N., Kersch, C. & Schmitz-Spanke, S. Identification and characterization of small ...
we describe how misregulated Polycomb proteins play a pleiotropic role in cancer by altering a broad spectrum of biological processes such as the proliferation-differentiation balance, metabolism and the immune response, all of which are crucial in tumor progression. ...
This review will summarize the current knowledge of how GPCRs are altered in cancer and how these aberrations can contribute to cancer initiation and progression. We also bring forth an emerging role of GPCRs as part of autocrine and paracrine signaling processes, which we refer to collectively ...
Deciphering the role of plasma proteins in pancreatic cancer (PC) susceptibility can aid in identifying novel targets for diagnosis and treatment. We examined the relationship between genetically determined levels of plasma proteins and PC through a syst
cancer are discussed. We describe existing and emerging roles as well as molecular mechanisms in supporting key biological processes in cancer emergence, with special emphasis on the anterior gradient (AGR) subfamily. In addition, the relevance and therapeutic strategies targeting the PDIs are ...
The drug is designed to treat patients with a form of acute myeloid leukemia in which the enzyme isocitrate dehydrogenase 1 (IDH1) is mutated, researchers at the University of Texas MD Anderson Cancer Center said. IDH1 mutations occur in 6 to 10 percent of AML patients. ...
Research was funded by grants from the National Institute of General Medical Sciences, grant or award numbers: GM122480 and R35GM138348; Cancer Prevention and Research Institute of Texas, grant or award number: RR160088; National Science Foundation, grant or award number: 2019238253; National ...
Combining anchor and distribution-based methods to derive minimal clinically important differences on the Functional Assessment of Cancer Therapy (FACT) anemia and fatigue scales. J Pain Symptom Manage. 2002;24(6):547-561.PubMedGoogle ScholarCrossref 42. Derogatis LR. Derogatis Affects Balance ...
Protein lysine methyltransferases (PKMTs) play crucial roles in histone and nonhistone modifications, and their dysregulation has been linked to the development and progression of cancer. While the majority of studies have focused on the oncogenic functions of PKMTs, extensive evidence has indicated th...
Although alterations in chromatin structure are known to exist in tumors, how these alterations relate to molecular phenotypes in cancer remains to be demonstrated. Multi-omics profiling of human tumors can provide insight into how alterations in chromat