posttranslational modificationPosttranslational modifications of protein, whether reversible or irreversible, play important roles in cell signaling. PTMs regulate protein activity, intracellular localization, stability, and protein-protein interactions. Major PTMs include phosphorylation, glycosylation, methylation...
3) post-translational modification 翻译后的蛋白质修饰4) protein modification 蛋白质修饰 例句>> 5) Chemical modification 蛋白质化学修饰6) nucleic acid/protein modified particles 核酸/蛋白质修饰补充资料:翻译后的蛋白质修饰 分子式:CAS号:性质:把某些从mRNA释译出来的蛋白质修饰加工成能被生物体细胞...
The elucidation of posttranslational modification of proteins is a prerequisite for understanding the molecular details of living organisms, from bacteria to plants and mammals. Protein phosphorylation plays a key role in cell signaling during cellular development, growth, and differentiation. Protein ...
Advanced molecular techniques have enumerated more than 200 posttranslational modifications and, in fact, many of them have been discovered recently. Posttranslational modifications can take place at any stage during the maturation of the protein, whereas other modifications usually take place after the ...
Posttranslational modification of proteins is an important way to regulate protein function. These modifications are crucial to the structure and function of proteins under physiological and pathological conditions. To date, approximately 50% ∼ 90% of proteins in human cells have different types...
Protein acetylation mechanisms in the regulation of insulin and insulin-like growth factor 1 signalling. Mol Cell Endocrinol. 2012;362:1–10. Article CAS PubMed Google Scholar Malik A, Afaq S, Alwabli AS, Al-Ghmady K. Networking of predicted post-translational modification (PTM) sites in ...
[30,31,32]. Protein phosphorylation is a sophisticated network consists of protein kinases, substrates, phospho-binding proteins and phosphatases [33,34,35,36,37]. During evolution, protein phosphorylation emerged as an essential and the most prevalent post-translational modification due to its ...
Protein phosphorylation (Figure 2) is the most commonly studied post-translational modification. It has been estimated that one-third of mammalian proteins may be phosphorylated, and this modification often plays a key role in modulating protein function. Phosphorylation takes place on serine, threonine...
Post translational modification(蛋白质翻译后修饰) 相关知识点: 试题来源: 解析 肽链合成的结束,并不一定意味着具有正常生理功能的蛋白质分子已经生成。已知很多蛋白质在肽链合成后还需经过一定的加工(processing)或修饰,由几条肽链构成的蛋白质和带有辅基的蛋白质,其各个亚单位必须互相聚合才能成为完整的蛋白质分子。
Protein S-nitrosation represents a recently described form of posttranslational modification that is rapid and reversible. However, the analysis of protein... Y Yang,J Loscalzo - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 263发表: 2005年 Nitro-fa...