Posttranslational modifications (PTMs) of proteins, the major mechanism of protein function regulation, play important roles in regulating a variety of cellular physiological and pathological processes. Although the classical PTMs, such as phosphorylation, acetylation, ubiquitination and methylation, have be...
Protein processing is required for the maturation of proteins and for activation and turnover. The ability to detect and monitor posttranslational modifications and processing of proteins by mass spectrometry and other analytical methods is already providing exciting insights into key regulatory events in...
Differential Post-Translational Modifications of Proteins in Bladder Ischemia Clinical and basic research suggests that bladder ischemia may be an independent variable in the development of lower urinary tract symptoms (LUTS). We hav... HP Choi,JH Yang,KM Azadzoi - 《Biomedicines》 被引量: 0发表...
More than 200 diverse types of PTMs are currently known (5,6), ranging from small chemical modifications (e.g., phosphorylation and acetylation) to the addition of complete proteins (e.g., ubiquitylation, Figure 3). Phosphorylation Protein phosphorylation (Figure 2) is the most commonly ...
Some of these modifications have been shown to be involved in the regulation of signal transduction pathways, metabolism and other biological processes. Abnormal regulation of proteins after translation is a common feature of human diseases. For example, lysine methylation is a common PTM that affects...
METHOD FOR MONITORING POST-TRANSLATIONAL MODIFICATION OF PROTEINS According to a method for monitoring post-translational modifications of protein is provided, a first microbead by binding a protein antibody to a base bea... SH Lee,JY Kang,MH Kim,... 被引量: 0发表: 2022年 In transgenic animal...
Due to the unique nature of spermatozoa, which are transcriptionally and translationally silent, the regulation of capacitation is based on the formation of posttranslational modifications of proteins (PTMs). However, the interactions between different t
13 Posttranslational 755 Modifications of Secretory Proteins. In: J.P.B. Alistair (Ed.)Methods in Microbiology 756 Yeast Gene Analysis. Volume 26 edn, Academic Press, pp. 223-238.Klis, F. M., Ram, A. F. J., Montijn, R. C., Kapteyn, J. C., Caro, L. H. P., Vossen, J. ...
Posttranslational Modifications of Proteins and Their Role in Biological Processes and Associated Diseases Irfan-ur-Rauf Tak, ... M.Z. Chishti, in Protein Modificomics, 2019 Abstract A posttranslational modification (PTM) depicts an imperative means for diversification and regulation of the cell...
Goat milk is a source of nutrition in difficult areas and has lesser allerginicity than cow milk. It is leading in the area for nutraceutical formulation and drug development using goat mammary gland as a bioreactor. Post translational modifications of a