With the many reviews of the area of post-translational modifications of proteins written in the course of the last 15 years (Alix and Hays, 1983; Krishna and Wold, 1992; 1993; Uy and Wold, 1977; Whitaker, 1977; Wold, 1981; 1983), there is little justification for just another review;...
Posttranslational modifications (PTMs) of proteins, the major mechanism of protein function regulation, play important roles in regulating a variety of cellular physiological and pathological processes. Although the classical PTMs, such as phosphorylation, acetylation, ubiquitination and methylation, have be...
Protein processing is required for the maturation of proteins and for activation and turnover. The ability to detect and monitor posttranslational modifications and processing of proteins by mass spectrometry and other analytical methods is already providing exciting insights into key regulatory events in...
Differential Post-Translational Modifications of Proteins in Bladder Ischemia Clinical and basic research suggests that bladder ischemia may be an independent variable in the development of lower urinary tract symptoms (LUTS). We hav... HP Choi,JH Yang,KM Azadzoi - 《Biomedicines》 被引量: 0发表...
Conditional chemical changes are relayed from sensors to effectors via reversible post-translational modifications (PTMs) of proteins. PTMs play an important part in modifying the end product of expression, contribute to biological processes and diseased conditions, playing a key role in many cellular...
This packaging of DNA imposes a severe restriction to proteins seeking access to DNA for DNA-templated processes such as transcription or replication. It is becoming increasingly clear that post-translational modifications of histone amino-termini play an important role in determining the chromatin ...
Articles collected from the meeting entitled Post- translational modifications of proteins and significance in cellular biochemistry, with was held in Osak... S Tsuboi,N Taniguchi,N Katunuma 被引量: 0发表: 0年 Diagnostic method based on large scale identification of post-translational modification of...
These alterations include DNA methylation, histone modifications, histone acetylation, and RNA interference [1]. Post-translational modification (PTM) of proteins is the chemical modification of specific amino acid residues, which is ubiquitous in mammalian cells and plays a crucial role in the ...
Breast cancer is the most prevalent malignant tumor and a leading cause of mortality among females worldwide. The tumorigenesis and progression of breast cancer involve complex pathophysiological processes, which may be mediated by post-translational modifications (PTMs) of proteins, stimulated by various...
A curated rotamer library for common post-translational modifications of proteins MOTIVATION. Sidechain rotamer libraries of the common amino acids of a protein are useful for folded protein structure determination and for generating ens... O Zhang,SA Naik,ZH Liu,... - 《Bioinformatics》...