POST-translational modificationAPELINPROTEIN synthesisSPINAL cordPROTEOLYSISPost-translational modifications (PTMs) are protein modifications that occur after protein biosynthesis, playing a crucial role in regulating protein function. They are involved in the functional expression of G-pr...
解析 posttranslational modification —翻译后修饰,新生多肽链不具备蛋白质的生物学功能,必须经过复杂的加工过程才能转变为具有天然构象的功能蛋白质,这一加工过程称为翻译后修饰。包括多肽链折叠为天然的三维构象及对肽链一级结构和空间结构的修饰等。反馈 收藏 ...
Post translational modification(蛋白质翻译后修饰) 相关知识点: 试题来源: 解析 肽链合成的结束,并不一定意味着具有正常生理功能的蛋白质分子已经生成。已知很多蛋白质在肽链合成后还需经过一定的加工(processing)或修饰,由几条肽链构成的蛋白质和带有辅基的蛋白质,其各个亚单位必须互相聚合才能成为完整的蛋白质分子。
图3. 早期阶段mAb生化和生物物理特性评估的一般流程 在mAb的生产过程中,不同的理化因素易产生各种翻译后修饰(post-translational modification,PTM)变异体,如糖基化、氧化、脱酰胺、异构化等,这些PTM可能引起抗体理化性质变化,这些变化会对mAb...
Post-translational modifications are modifications that occur on a protein, catalysed by enzymes, after its translation by ribosomes is complete. Post-translational modification generally refers to the addition of a functional group covalently to a protein as in phosphorylation and neddylation, but also...
Protein acetylation as a means to regulate protein function in tune with metabolic state. Protein acetylation has emerged as a prominent post-translational modification that can occur on a wide variety of proteins. The metabolite acetyl-CoA is a... L Shi,P Benjamin - 《Biochemical Society Transac...
1. 转译后修饰 1.转译后修饰(Post-Translational Modification)的介绍分子生物学中的中心法则:DNA→RNA→蛋白质,但是在生物体中许多蛋 … wedensbergpeng.wordpress.com|基于37个网页 2. 翻译后修饰 后修饰,Post... ... ) postmodifier 后置修饰 )post-translational modification翻译后修饰) postmodifiers 后置修饰...
Posttranslational modification of proteins is an important way to regulate protein function. These modifications are crucial to the structure and function of proteins under physiological and pathological conditions. To date, approximately 50% ∼ 90% of proteins in human cells have different types...
post-translational modification 翻译后修饰；译修饰 Sequence analysis of IL-2 showed that it had high homology with that of bubalus bubalis, except the difference of post-translational modification.序列分析表明，林麝IL-2及其受体结合域与水牛的高度保守，而在翻译后修饰的预测活性位点上和水牛的...
2.1.2.5 Posttranslational modifications Posttranslational modification (PTM) is an important biological process that diversifies the function of a protein. PTM occurs through the covalent addition of one or more functional groups on a protein or proteolytic cleavage or degradation of a protein catalyzed...