HNT-TCR转基因小鼠 1. To solve this problem, we adopted the HNT-TCR transgenic mice which have homogenous antige. 本文利用HNT-TCR转基因小鼠高度单一的针对HA多肽抗原的CD4+T细胞群体,以T细胞增殖反应作为检测方法,比较研究了克隆CD4+T细胞和新提取未经刺激的CD4+T细胞对无能诱导的反应。6...
Specifically, melanocyte-reactive T cells were detected by immunostaining for the Vβ12 TCR subunit in Pmel-1 mouse skin. The mice were treated with the PD-L1 fusion protein for 6 weeks and harvested 1 week after the final treatment (n = 6). The numbers of TCR-positive cells were ...