Furthermore, Tregs abundance was also increased in both the spleen and circulation of Pmel-1 mice treated with PD-L1. These data indicate that PD-L1 protein therapy inhibits the immune response and reverses depigmentation development in Pmel-1 vitiligo mice....
可能和OT-1 mice sacrifice 得到的OT-1 T 细胞一样？PMELCD8+ T细胞能够特异性识别黑色素瘤B16F10肿...
可能和OT-1 mice sacrifice 得到的OT-1 T 细胞一样？PMELCD8+ T细胞能够特异性识别黑色素瘤B16F10肿...
9 In mice, the allele Mitfmi leads to complete absence of melanocytes in the homozygous state,10 while mice homozygous for Mitfvit (vitiligo) are born with a nearly normal coat color, but turn white over the first few months of life as melanocytes are lost, suggesting a role for MITF in...
We previously reported that addition of NX-0255 during in vitro treatment of tumor-specific T cells increases the frequency and absolute numbers of less exhausted CD8+ memory T cells, profoundly improving their functionality and ability to control tumor growth following ACT in tumor-bearing mice. He...
Naïve B16 specific Pmel-1 T cells are primed by tumor growth and infiltrate tumors after adoptive transfer into tumor bearing mice.David, A. SchaerYongbiao, LiTaha, MerghoubGabrielle, A. RizzutoAmos, ShemeshAdam, D. CohenYanyun, Li
PMELCD8+ T细胞能够特异性识别黑色素瘤B16F10肿瘤细胞的gp100抗原OT-1 CD8+ T细胞能够特异性识别OVA ...
看文献里看到的 ， 文献里是 Pmel-1 derived Tc1。这个细胞有什么特别的吗？谢谢可能和OT-1 mice...