especially in cancer cells with mutated SET domain containing 2 (SETD2), a histone H3 lysine 36 (H3K36) trimethyltransferase [99]. Except for CREB, the cAMP/PKA-regulated phosphoprotein DARPP-32 enhances ERBB3/EGFR heterodimerization and promotes EGFR inhibitor resistance in EGFR-mutated lung...
PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B Nat. Cell Biol., 13 (2011), pp. 668-675 CrossrefView in ScopusGoogle Scholar Bachmann et al., 2016 V.A. Bachmann, J.E. Mayrhofer, R. Ilouz, P. Tschaikner, P. Raffeiner, R. Rock, M. Courcelles, F....
In the case of BBSV, recent studies have demonstrated that an N-terminal region enriched in basic amino acids (4KRNKGGKKSR13) is involved in CP nuclear locali- zation and gRNA binding, and that lysine and arginine at positions 4 and 5 are key amino acid require- ments for gRNA binding...
Like other AGC kinases, it is basophilic and its limited number of known substrates suggest a preference for arginines and, to a lesser extent, lysines in the P-3 and P-2 positions [24,25]. It is phosphorylated by TORC1 on six serine and threonine residues near its C-terminus that ...
Cβ-aectliln viability and induction of apopFitgousirse w2.aIsL-m24eascutirveadtesbypr3o-t(e4in,5k-dinimasetAhy(lPtKhiAa)zoinl-a2-cyoln)-c2e,n5t-rdaitpiohne-dneyplteentdraeznot lmiuamnnebrr.o(mA)idMeCMF-T7T and annecexlilns wVe-rfelutoreraetsecdeifnori7so2thhiwoictyhaAndat.IeL...