Park SC, Cho KA, Jang IS, Kim KT, Ryu SJ (2004) Functional efficiency of the senescent cells: replace or restore. Ann NY Acad Sci 1019:309–316Park SC (2004) Phenotypic adjustment of senescent cells: replace or restore. Geriatr Gerontol Int 4:517–520...
Cerebellum locates in the hindbrain region and consists of highly dense and complex neuron networks in the human brain1. It is challenging to derive human brain cerebellar-like spheroids/organoids with similar biomarkers and function from human pluripotent stem cells (hPSCs), including both human ind...
Baseline characteristics The baseline characteristics of a total of 2580 participants from the United States are presented in Table 1. Individuals exhibiting PhenoAgeAccel tended to be older; identify as Hispanic; and have elevated BMI, HbA1c, insulin, waist circumference, abdominal SFA, and VFA. ...
Common variable immunodeficiency (CVID) is a heterogeneous group of diseases. Our aim was to define sub-groups of CVID patients with similar phenotypes and clinical characteristics. Using eight-color flow cytometry, we analyzed both B- and T-cell phenotypes in a cohort of 88 CVID patients and ...
These cells were defined CSCs because they share with stem cells biological characteristics like the unlimited capability to grow3. This observation changes completely the therapeutic perspective since the only way to eradicate the tumor is to target CSCs28. Yet, the identification of the best ...
Endurance flight impose substantial oxidative costs on the avian oxygen delivery system. In particular, the accumulation of irreversible damage in red blood cells can reduce the capacity of blood to transport oxygen and limit aerobic performance. Many so
ed pulmonary vascular remodeling is accompanied by the acquisition and maintenance of a modified pro-proliferative apoptosis-resistant phenotype in the various contractile vascular cells in the arterial wall, including PA-SMCs, adventitial fibroblasts, and cells expressing myofibroblast-like characteristics....
However, punctuated growth patterns, one of the common characteristics of the nwt phenotype, were observed 10 to 16 weeks after they were placed in race tubes and monitored (see below). Validation of experimentally induced phenotypic conversion by means of global mRNA profiling...
Park SC, Cho KA, Jang IS, Kim KT, Ryu SJ (2004) Functional efficiency of the senescent cells: replace or restore. Ann NY Acad Sci 1019:309–316Park SC (2004) Phenotypic adjustment of senescent cells: replace or restore. Geriatr Gerontol Int 4:517–520...
Stem cells have unique metabolic characteristics that play an essential role in maintaining their self-renewal and multi-potentiality. Human mesenchymal stem cells (hMSCs) are a primary cell source in cell therapy for a wide range of diseases. However, culture induced changes in hMSC phenotype ...