Potassium channels constitute the largest and most ubiquitous and diverse ion channel family. They regulate several physiological processes including electrical signalling, hormone and neurotransmitter release, muscle contraction, cardiac function, cell proliferation and immune function, which are underscored by...
Pharmacology of potassium channels . Adv Pharmacol 39 , 425 – 471 .Garcia, M.L., Hanner, M., Knaus, H.G., Koch, R., Schmalhofer, W., Slaughter, R.S. & Kaczorowski, G.J. (1997) Pharmacology of potassium channels. Adv. Pharmacol. 39, 425±471....
The Pharmacology of ATP-Sensitive Potassium Channels Annu Rev Pharmacol Toxicol. 1993;33:597-637. Research Support, Non-U.S. Gov't; Review G Edwards,AH Weston - 《Annual Review of Pharmacology & Toxicology》 被引量: 1296发表: 1993年 Potassium channels and pain: present realities and future ...
The cardiac action potential results from the complex, but precisely regulated, movement of ions across the sarcolemmal . channels represent the most diver... KK Deal,SK England,MM Tamkun - 《Physiological Reviews》 被引量: 479发表: 1996年 Interaction of different potassium channels in cardiac re...
As these channels become inactivated, potassium channels open (increased gK) permitting potassium ions to leave the cell, which causes repolarization of the membrane potential (phases 3 and 4). Potassium channels remain open until the next action potential is triggered. A different type of potassium...
[6] Wulff, H., Castle, N. A., & Pardo, L. A. (2009). Voltage-gated potassium channels as therapeutic targets.Nature Reviews. Drug Discovery, 8(12), 982–1001. [7] Cheng, N., Ren, S., Yang, J.-F., Liu,...
Physiology and Pharmacology of Two-Pore Domain Potassium Channels Searching the DNA database has led to the identification of a class of K+ channels now referred to as two-pore or tandem-pore domain K+ (K2P) channels. The... Donghee,Kim - 《Current Pharmaceutical Design》 被引量: 258发表...
ATP-sensitive potassium channels (KATP) are widely distributed and present in a number of tissues including muscle, pancreatic beta cells and the brain. Th... A Tinker,Q Aziz,A Thomas - 《British Journal of Pharmacology》 被引量: 59发表: 2014年 ...
Voltage-operated Ca2+ channels are complex membrane proteins that are responsible for mediating Ca2+ influx in response to membrane depolarization (Hille 1984). Ca2+ entry through these channels serves to regulate intracellular processes such as contract
Structure-activity studies on scorpion toxins that block potassium channels: A. L. Harvey,1H. Vatanpour,1E. G. Rowan,1C. Vita2 and M.-F. Martin-Eauclaire3 (1Department of Physiology and Pharmacology, Strathclyde University, Glasgow, U.K... The effect of temperature on phospholipase A2 ...