参考文文献:Yi M, Niu M, Xu L, Luo S, Wu K. Regulation of PD-L1 expression in the tumor microenvironment. J Hematol Oncol. 2021 Jan 7;14(1):10. doi: 10.1186/s13045-020-01027-5. PMID: 33413496; PMCID: PMC7792099. 举报/反馈 发表评论 发表 评论列表(5条) 百里杜鹃的天空86e 似...
[15] Zhou YJ, Li G, Wang J, et al. PD-L1: expression regulation. Blood Sci. 2023;5(2):77-91. Published 2023 Jan 13. doi:10.1097/BS9.0000000000000149 [16] Patel SP, Kurzrock R. PD-L1 Expression as a Predictive Biomarker in Cancer Immunotherapy. Mol Cancer Ther. 2015;14(4):847-...
2015, 3(12): 1375-1385.DOI: 10.1158/2326-6066.Cir-15-0077-t.HoggSJ, VervoortSJ, DeswalS, et al.BET-bromodomain inhibitors engage the host immune system and regulate expression of the immune checkpoint ligand PD-L1
In addition, various nuclear receptors, such as androgen receptor, estrogen receptor, peroxisome-proliferator-activated receptor 纬, and retinoic-acid-related orphan receptor 纬, also regulate the expression of PD-L1. This review will focus on the current knowledge of the regulation of PD-L1 ...
However, as there is limited information on how programmed death ligand-1 is upregulated on tumor cells within the tumor microenvironment, we examined the mechanism of programmed death ligand-1 regulation with a particular focus on interferon gamma in an invitro setting and in clinical samples. ...
原文链接:Immunorthodontics: Role of HIF-1α in the Regulation of (Peptidoglycan-Induced) PD-L1 Expression in Cementoblasts under Compressive Force - PubMed 小编旨在分享、学习、交流生物科学等领域的研究进展。如有侵权或引文不当请联系小编修正。 微信搜索公众号“Naturethink”,了解更多细胞体外仿生培养技术...
5.Kowanetz M, Zou W, Gettinger S N, et al. Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti–PD-L1)[J]. Proceedings of the National Academy of Sciences, 2018, 115(43): E10119-E10126.6.Garon E B, ...
The important discovery that programmed death ligand 1 (PD-L1) expression on tumor cells inhibits programmed cell death 1 (PD-1) on T cells to escape immune surveillance has opened an era of tumor immunotherapy1,2,3,4. PD-L1 is a type I transmembrane protein5containing an extracellular doma...
Up-regulation of PD-L1 expression promoted the proliferation of EoL-1. At 48 and 72 h after seeding, the proliferation rate of OE-PD-L1 group was significantly higher than that of the vector group. (E) Knockdown of PD-L1 expression promotes cell apoptosis in KG-1a cell lines. (F) ...
(2012).12. Shao, S. et al. Multiplexed sgRNA Expression Allows Versatile Single Nonrepetitive DNA Labeling and Endogenous Gene Regulation. ACS Synth Biol 7, 176-186 (2018).（可上下滑动阅览）原标题：《【学术前沿】康铁邦/武远众团队揭示阻断KAT8-IRF1凝聚体形成可抑制PD-L1表达并增强抗肿瘤免疫》