Pathophysiology of bone cancer pain. The most common cancers, such as those affecting the breast, prostate, and lung have a strong predilection to metastasize to bone. Bone metastasis frequently results in pain, pathologic fractures, hypercalcemia, and spinal cord compressi... MAC Sabino,PW Mantyh...
Human epidermal growth factor receptor 2 (HER2) is overexpressed in around 20-30% of breast cancer tumors. It is associated with a more aggressive disease, higher recurrence rate, and increased mortality. Trastuzumab is a HER2 receptor blocker that has become the standard of care for the ...
et al. A microfluidic 3D in vitro model for specificity of breast cancer metastasis to bone. Biomater. 35, 2454–2461 (2014). 13. Ehsan, S. M., Welch-Reardon, K. M., Waterman, M. L., Hughes, C. C. & George, S. C. A three-dimensional in vitro model of tumor cell intravas...
The book contains images of seminude breast cancer survivors of all ages photographed by Art Myers, DO, MPH, accompanied by "original poetry and subject-written vignettes." Reproduced by permission. This is the second edition of what must already be considered the standard textbook of pediatric ...
FGF receptors (FGFRs) are involved in the pathogenesis of cancer and skeletal disorders. Experiments in model systems have shown that FGFR-specific inhibitors may be valuable in treating multiple myeloma, bladder and endometrial cancers. FGF1, FGF2 and FGF4 have been studied in clinical trials fo...
Rogers. Gut microbiota diversity is associated with cardiorespiratory fitness in post‐primary treatment breast cancer survivors. Experimental Physiology 2019; 104(4): 529 doi: 10.1113/EP087404 118 Ivana Milosevic, Ankica Vujovic, Aleksandra Barac, Marina Djelic, Milos Korac, Aleksandra Radovanovic ...
T cells with a chimeric antigen receptor (CAR) specific for HERV-K (HML-2) Env protein (K-CAR) can greatly decrease the proliferation of breast cancer cells and cytotoxicity [108]. In xenograft experiments, K-CAR significantly inhibited tumor growth and metastasis to other organs. Anti-HERV-...
Trending Audio Highlights JAMA This Week in JAMA December 13, 2024 Reimagining Luck JAMA A Piece of My Mind December 13, 2024 Camrelizumab vs Placebo With Chemotherapy as Neoadjuvant Treatment in Triple-Negative Breast Cancer JAMA Original Investigation December 13, 2024...
1. Cancer-related anorexia-cachexia 2. Anorexia 3. Cachexia 4. Cancer anorexia-cachexia in special populations 5. Pathogenesis of anorexia 6. Interleukin 1 7. Tumor necrosis factorα 8. Interleukin 6 9. Peripheral hormones in cancer anorexia 10. Leptin 11. Ghrelin 12. Neuropeptide Y 13. Pharm...
In vivo two-photon imaging is a valuable technique for studies of viral pathogenesis and host responses to infection in vivo. In this protocol, we describe a methodology for analyzing influenza virus–infected lung in vivo by two-photon imaging microscop