Sex Hormone-Binding Globulin (SHBG) also plays a crucial role in the pathophysiology of breast cancer, primarily by regulating circulating estradiol [26]. Consequently, a decrease in SHBG levels is associated with a higher risk of breast cancer development. Additionally, androgens, such as ...
Long non-coding RNAs (lncRNAs) involved in metabolism are recognized as significant factors in breast cancer (BC) progression. We constructed a novel prognostic signature for BC using metabolism-related lncRNAs and investigated their underlying mechanism
Microcalcifications in breast cancer: from pathophysiology to diagnosis and prognosis. Biochim Biophys Acta Rev Cancer. 2018;1869:310–20. Article CAS Google Scholar Mazari FAK, Sharma N, Dodwell D, Horgan K. Human epidermal growth factor 2-positive breast cancer with mammographic microcalcification...
It is difficult to accurately assess axillary lymph nodes metastasis and the diagnosis of axillary lymph nodes in patients with breast cancer is invasive and has low-sensitivity preoperatively. This study aims to develop a mammography-based radiomics nomogram for the preoperative prediction of ALN meta...
[43]. PPAR signaling has implications in the pathophysiology of skeletal muscle dysfunction in patients with breast cancer [44]. RGZ activates PPARg signaling in endothelial cells [45]. RGZ inhibits metastasis and migration, decreases MMP-2 expression, and prevents angiogenesis by blocking the ...
We counsel our triple-negative breast cancer (TNBC) patients that the risk of recurrence is highest in the first 5 years after diagnosis. However, there are limited data with extended follow-up on the frequency, characteristics, and predictors of late ev
Breast cancer (BC) is one of the major public health challenges worldwide. Studies that address the new evidence on trends of BC are of great importance for preventing and controlling the occurrence and development of diseases and improving health. The aim of this study was to analyze the outc...
Furthermore, our preliminary hyperthermia examination on MCF7 cells at 0.35 mg/mL concentration of magnetic fluid revealed an increased sensitivity of breast cancer cells against hyperthermia during initial phase itself where a 60 min HT without MF led to more than 50% cell death compared to contro...
The search strategy used Medical Subject Headings (MeSH) terms: “sacituzumab govitecan”, “breast cancer”, “triple negative breast cancer”, “guidelines”, “UGT1A1”, “clinical trial”, “HR”, and “adverse events”. These terms were combined using the Boolean operators “AND”, “...
Adhesive capsulitis of the shoulder causes chronic pain, and its pathophysiology after breast cancer surgery is complex. Despite the uncertainty of the pathophysiologic mechanism of adhesive capsulitis, capsular fibrosis and reductions in capsular volume after synovial inflammation are considered to be the...