Breast cancer brain metastasismiRNABrain tumor microenvironmentBlood-brain barrierCNS metastasismiRNAs mediated regulation of BCBMdoi:10.1186/s12943-020-1140-xRanjana K. KanchanJawed A. SiddiquiSidharth MahapatraSurinder K. BatraMohd W. NasserMolecular Cancer...
Abstract Matrigel, a mouse sarcoma-derived basement membrane protein mixture, is frequently used to facilitate human tumor xenograft growth in rodents. Despite its known effects on tumor growth and metastasis, its impact on tumor pathophysiology and preclinical evaluation of nanomedicines in tumor xenograf...
growth Mohammad Reza Nikmaneshi1,2, Bahar Firoozabadi2*, Aliasghar Mozafari2 & Lance L. Munn1* The search for efficient chemotherapy drugs and other anti-cancer treatments would benefit from a deeper understanding of the tumor microenvironment (TME) and its role in tumor ...
The most common cancers, such as those affecting the breast, prostate, and lung have a strong predilection to metastasize to bone. Bone metastasis frequently results in pain, pathologic fractures, hypercalcemia, and spinal cord compression. Pain can have a devastating effect on the quality of life...
Hematological malignancies rarely affect the breast, and the majority of those that do are lymphomas. In this review, we describe the clinical aspects and ... S Euddeum,SE Song,SB Kyoung,... - 《Journal of Breast Cancer》 被引量: 42发表: 2013年 Phyllodes Tumor of the Breast: Magnetic Re...
Gynaecomastia (enlargement of the male breast tissue) is a common finding in the general population. Most cases of gynaecomastia are benign and of cosmetic, rather than clinical, importance. However, the condition might cause local pain and tenderness, could occasionally be the result of a seri...
Tumor cell disseminating from patients with breast or prostate cancer typically use the bony environment to grow outside the primary tumor location. The severe clinical consequences of bone metastasis such as pain, fractures, and hypercalcemia result from a serious misbalance of bone turnover. Most ...
Bone is a frequent site of involvement in patients with prostate cancer, breast cancer and multiple myeloma (MM) because the propensity of these tumors to home to bone and the capacity of bone marrow to support the growth of the tumor. In patients with osteolytic and osteoblastic bone ...
Tumor Microbiome Differs in Young- vs Average-Onset CRC Breast Cancer e-Tumor Boards: Case 5: Metastatic High-Grade Neuroendocrine Carcinoma NUT Carcinoma: Diagnostic Challenges, Emerging Treatments, and Clinical Trials Word Choice and Royals: The Need To Be Clear and Precise Tools Drug Intera...
The expression of Hypoxia Inducible Factor-2-alfa (HIF-2α), a key regulator in RCC development, was increased by 3.9 ± 1.2-fold. The efflux drug transporter Breast Cancer Resistance Protein (BCRP), associated with resistance to chemotherapeutical agents, was upregulated by 9.4 ±...