The pathologist is involved at various steps in the management of patients with breast cancer, beginning with the confirmation of malignancy and ending with the establishment of prognostic and predictive markers. A close collaboration between surgeons and pathologists is mandatory for proper diagnostics ...
Review of comparative pathology studies of breast cancer among Japanese women and other ethnic groups reveals consistent differences in tumor morphology and host response. Japanese women show lower rates of breast cancer than Caucasian women, a difference that is accounted for by increased rates of thi...
A small proportion of breast-cancer cases, in particular cancers diagnosed in young patients are attributable to a hereditary predisposition to the disease, which is transmitted as a highly penetrant autosomal dominant trait. There has been considerable progress in the identification of the genes respon...
et al. A single-cell atlas of the tumor and immune ecosystem of human breast cancer. Cell 177, 1330–1345 (2019). Article CAS PubMed PubMed Central Google Scholar Bedard, P. L., Hansen, A. R., Ratain, M. J. & Siu, L. L. Tumour heterogeneity in the clinic. Nature 501, 355...
If we want to evaluate the contribution of immunohistochemistry to the understanding of breast disease, we must first consider the role of histopathology. The aims of histopathological studies are: 1. differentiation between benign and malignant lesions. 2. classification and grading of malignancy (rele...
Molecular Pathology of Breast Cancer 来自 学术范 喜欢 0 阅读量: 8 作者: KH Allison 摘要: Pathologists are now more than ever "diagnostic oncologists" and serve a critical role as clinical consultants on the biology of disease. In the last decade and a half, molecular information has ...
Review of comparative pathology studies of breast cancer among Japanese women and other ethnic groups reveals consistent differences in tumor morphology and host response. Japanese women show lower rates of breast cancer than Caucasian women, a difference that is accounted for by increased rates of thi...
Scientists have discovered a previously unknown mechanism by which estrogen prepares cells to divide, grow and, in the case of estrogen-positive breast cancers, resist cancer drugs. The researchers say the work reveals new targets for breast cancer thera
Pathology and Epidemiology of Cancer || Pathology and Molecular Pathology of Breast Cancer The multistep model of carcinogenesis in the breast suggests a transition from normal epithelium to invasive carcinoma via non-atypical and atypical hyperplasia and in situ carcinoma. The introduction of mammographi...
Cancer orCarcinomais a group ofdiseasesinvolvingabnormal cellular growthand division. When cells startproliferatingrapidly in an uncontrolled manner in the breast, it is calledBreast Cancer. Signs of breast cancer may include alumpin the breast, a change inbreast shape,dimplingof the skin fluid coming...