Fibrosis is defined as a fibroproliferative or abnormal fibroblast activation-related disease. Deregulation of wound healing leads to hyperactivation of fibroblasts and excessive accumulation of extracellular matrix (ECM) proteins in the wound area, the pathological manifestation of fibrosis. The accumulation...
特发性肺纤维化(idiopathic pulmonary fibrosis,IPF)是一种原因不明的慢性,进行性间质性疾病.起病引袭,自然病程持续进展,临床上以进行性呼吸困难和低氧血症为主要特征.IPF的基础病因目前还不清楚,以往的研究多认为与多种细胞因子如:转化生长因子-β(TGF-β),肿瘤坏死因子-α(TNF-α),血小板源性生长因子(PDGF)...
Studies have shown PAI-1 to be also involved in fibrosis. 包装清单: 产品编号 产品名称 包装 AF7965 PAI-1/SERPINE1 Rabbit Polyclonal Antibody 50μl AZ050 Western一抗稀释液 50ml — 说明书 1份 保存条件: PAI-1/SERPINE1 Rabbit Polyclonal Antibody -20ºC保存,Western一抗稀释液-20º...
14.Yoshiji H, Kuriyama S, Yoshii J, Ikenaka Y, Noguchi R, Nakatani T, Tsujinoue H, Yanase K, Namisaki T, Imazu H. Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse.Hepatology. 2002;36:850-860.[PubMed][DOI] ...
B. Fogo, "PAI-1 and kidney fibrosis," Frontiers in Bioscience, vol. 14, no. 6, pp. 2028-2041, 2009.Ma LJ; Fogo AB.PAI-1 and kidney fibrosis.Front Biosci.2009.41-2028MA, L. J.; FOGO, A. B. PAI-1 and kidney fibrosis. Frontiers in bioscience (Landmark edition), v. 14, p....
The PA-Plasmin system is involved in fibrinolysis, tissue fibrosis, angiogenesis, wound healing, tumor cell invasion and metastasis, and obesity... Show More Filters: Proteins and Enzymes Clear All X Recombinant Human Serpin E1/PAI-1 Protein, CF Best Seller Catalog #: 1786-PI (1) Citatio...
METHODS:Liverfibrosiswasinducedinrats byintraperitonealinjectionofDMN.Allrats weresacrificedtotakelivertissuespecimens. Formalin-fixedliversectionswerestainedwith hematoxylinandeosin(HE)andSiriusRedto evaluategeneralhistologyandhepaticfibrosis, respectively.TheexpressionofOPNandPAI-1 ...
Identification of Impacted Pathways and Transcriptomic Markers as Potential Mediators of Pulmonary Fibrosis in Transgenic Mice Expressing Human IGFBP5. Authors - Xinh-Xinh Nguyen View Article human WB Am J Respir Cell Mol Biol ZMPSTE24 Regulates SARS-CoV-2 Spike Protein-enhanced Expression of Endotheli...
Inhibition of Plasminogen Activator Inhibitor-1 Its Mechanism and Effectiveness on Coagulation and Fibrosis[J]. Arteriosclerosis Thrombosis and Vascular Biology, 2008, 28(4):672-677.2.Izuhara Y , Yamaoka N , Kodama H , et al. A novel inhibitor of plasminogen activator inhibitor-1 provides ...