参考文献: Jamieson, Amy et al. “Clinical Behavior and Molecular Landscape of Stage I p53-abnormal Low-Grade Endometrioid Endometrial Carcinomas.”Clinical cancer research : an official journal of the American Association ...
参考文献: Jamieson, Amy et al. “Clinical Behavior and Molecular Landscape of Stage I p53-abnormal Low-Grade Endometrioid Endometrial Carcinomas.”Clinical cancer research : an official journal of the American Association for Cancer Research, 10.1158/1078-0432.CCR-23-1397. 29 Sep. 2023,doi:10.115...
--p53异常过表达(p53 abnormal overexpression, OE):通常是TP53的错义突变,突变位点通常在DBD的中心位置 --p53异常完全缺失(p53 abnormal complete absence, CA):通常是TP53发生无义、移码、剪接或缺失突变,导致p53免疫组化所用抗体无法识别的突变p53的抗原表位,表现为IHC阴性 --p53异常胞浆着色(p53 abnormal cytopl...
参考文献: Jamieson, Amy et al. “Clinical Behavior and Molecular Landscape of Stage I p53-abnormal Low-Grade Endometrioid Endometrial Carcinomas.”Clinical cancer research : an official journal of the American Association for Cancer Research, 10.1158/1078-0432.CCR-23-1397. 29 Sep. 2023,doi:10.115...
Jamieson, Amy et al. “Clinical Behavior and Molecular Landscape of Stage I p53-abnormal Low-Grade Endometrioid Endometrial Carcinomas.”Clinical cancer research : an official journal of the American Association for Cancer Research, 10.1158/1078-0432.CCR-23-1397. 29 Sep. 2023,doi:10.1158/1078-043...
Among the 4 molecular subgroups of endometrial carcinoma, the p53 abnormal (copy number high) subgroup has the worst prognosis; however, the histologic characteristics of this subgroup are not well established. Also, it is not well established whether low-grade tumors can belong to the p53 ...
Jamieson, Amy et al. “Clinical Behavior and Molecular Landscape of Stage I p53-abnormal Low-Grade Endometrioid Endometrial Carcinomas.”Clinical cancer research : an official journal of the American Association for Cancer Research, 10.1158/1078-0432.CCR-23-1397. 29 Sep. 2023,doi:10.1158/1078-043...
XY-E11469【中文名称】人异常凝血酶原(APT)ELISA试剂盒品牌【英文名称】Human Abnormal prothrombin,APT ELISA试剂盒多少钱 XY-E11470【中文名称】人循环免疫复合物(CIC)ELISA试剂盒品牌【英文名称】Human circulating immune complex,CIC ELISA试剂盒多少钱
--p53异常完全缺失(p53 abnormal complete absence, CA):通常是TP53发生无义、移码、剪接或缺失突变,导致p53免疫组化所用抗体无法识别的突变p53的抗原表位,表现为IHC阴性 --p53异常胞浆着色(p53 abnormal cytoplasmic pattern, CY):伴或不伴核染色。近几年妇科上皮性肿瘤中见研究报道,是TP53核定位域(即前文介绍的...
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